Your session is about to expire
← Back to Search
Neurotoxin
Botulinum Toxin Injections for Wrinkles
N/A
Waitlist Available
Led By Murad Alam, MD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at baseline and at 6 months
Awards & highlights
Study Summary
This trial will compare Botox and Xeomin to see which is more effective in reducing forehead and glabellar wrinkles.
Who is the study for?
This trial is for healthy adults aged 20-65 with moderate forehead and glabellar wrinkles who can give informed consent. It's not for those under 20 or over 65, pregnant/lactating women, people with bleeding disorders, mental illness, recent cosmetic procedures in the treatment area, or allergies to cow's milk protein or albumin.Check my eligibility
What is being tested?
The study compares Botox® (Onabotulinum Toxin A) and Xeomin® (Incobotulinum Toxin A) to see which is more effective at treating forehead and glabellar wrinkles. Participants will receive injections of either product.See study design
What are the potential side effects?
Possible side effects include pain at the injection site, headache, bruising or swelling where injected, drooping eyelids or eyebrows if the toxin spreads from the injection site.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ at baseline and at 6 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at baseline and at 6 months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in forehead wrinkle score from baseline to 6 months for botox vs. xeomin
Change in glabellar wrinkle score from baseline to 6 months for botox vs. xeomin
Trial Design
2Treatment groups
Active Control
Group I: Onabotulinum Toxin AActive Control1 Intervention
One side of the face will be randomized to receive Onabotulinum Toxin A injections in the forehead and glabellar region of the face.
Group II: Incobotulinum Toxin AActive Control1 Intervention
The other side of the face will be randomized to receive Incobotulinum Toxin A injections in the glabellar and forehead region of the face.
Find a Location
Who is running the clinical trial?
Northwestern UniversityLead Sponsor
1,585 Previous Clinical Trials
917,211 Total Patients Enrolled
2 Trials studying Wrinkles
24 Patients Enrolled for Wrinkles
Murad Alam, MDPrincipal InvestigatorNorthwestern University
69 Previous Clinical Trials
2,560 Total Patients Enrolled
2 Trials studying Wrinkles
24 Patients Enrolled for Wrinkles
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You are between 20 and 65 years old.Both females and malesYou are in generally good physical condition.You have noticeable wrinkles on your forehead and between your eyebrows.You have a history of problems with bleeding.You have a mental illness.You have received a treatment with a special device on your forehead or between your eyebrows in the past 6 months.You have had a medium to deep chemical peel on your forehead or between your eyebrows in the last 6 months.You are planning to use tretinoin or retinoic acid in the next 6 months.You are allergic to proteins found in cow's milk.You are allergic to albumin, a type of protein.You are currently taking medication to prevent blood clots.You have had injections of a substance called botulinum toxin in your forehead or between your eyebrows within the last 6 months.You have received a treatment using an ultrasound device on your forehead or the area between your eyebrows within the past 6 months.
Research Study Groups:
This trial has the following groups:- Group 1: Onabotulinum Toxin A
- Group 2: Incobotulinum Toxin A
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Who else is applying?
What state do they live in?
Louisiana
Indiana
Illinois
How old are they?
18 - 65
What site did they apply to?
Northwestern University Department of Dermatology
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
2
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger