Treatment for Wrinkles

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Northwestern University Department of Dermatology, Chicago, IL
Wrinkles
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether Botox® or Xeomin® is more effective for the treatment of forehead and glabellar (vertical lines between the eyebrows) wrinkles.

See full description

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 2 primary outcomes in patients with Wrinkles. Measurement will happen over the course of At baseline and at 6 months.

Month 6
Change in forehead wrinkle score from baseline to 6 months for botox vs. xeomin
Change in glabellar wrinkle score from baseline to 6 months for botox vs. xeomin

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Incobotulinum Toxin A
1 of 2
Onabotulinum Toxin A
1 of 2
Active Control

This trial requires 20 total participants across 2 different treatment groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Incobotulinum Toxin A
Drug
The other side of the face will be randomized to receive Incobotulinum Toxin A injections in the glabellar and forehead region of the face.
Onabotulinum Toxin A
Drug
One side of the face will be randomized to receive Onabotulinum Toxin A injections in the forehead and glabellar region of the face.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: at baseline and at 6 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly at baseline and at 6 months for reporting.

Who is running the study

Principal Investigator
M. A.
Prof. Murad Alam, Professor in Dermatology, Otolaryngology - Head and Neck Surgery, and Surgery-Organ Transplantation
Northwestern University

Closest Location

Northwestern University Department of Dermatology - Chicago, IL

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 5 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
In good health
Is 20-65 years of age
Has static and moderate dynamic forehead/glabellar wrinkles
Has willingness and the ability to understand and provide informed consent and communicate with the study staff
Females and males

Patient Q&A Section

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Other questions from users

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any geographic restrictions to consider when applying for this trial?

Patients from any state can participate in this trial, so long as they are able to attend all treatment sessions.

Will my insurance cover participating in this trial?

In order to understand how insurance coverage works for this trial, you will need to contact the study coordinator.

See if you qualify for this trial
Get access to this novel treatment for Wrinkles by sharing your contact details with the study coordinator.