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Behavioral Intervention

Telehealth for HIV Prevention (CHARIOT Trial)

N/A

Waitlist Available

Led By Hansel Tookes, MD

Research Sponsored by University of Miami

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 12 months

Awards & highlights

CHARIOT Trial Summary

This trial will compare 2 ways of giving meds to prevent HIV, cure HCV & treat substance use disorder in people who inject drugs.

Who is the study for?

This trial is for English-speaking adults over 18 who use syringe services and plan to stay local for a year. They must test negative for HIV, not be on opioid meds or HIV prevention drugs, and can't be in jail or other trials.Check my eligibility

What is being tested?

The study tests two methods of delivering medications to prevent HIV, possibly cure HCV, and treat substance use if desired—all through telehealth services aimed at people who inject drugs.See study design

What are the potential side effects?

While specific side effects are not listed here, participants may experience issues related to the preventive medications for HIV/HCV and treatments for substance use disorder provided via telehealth.

CHARIOT Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

HIV prevention via medications for opioid use disorder

HIV prevention via pre-exposure prophylaxis (PrEP)

Secondary outcome measures

HCV cure

acceptance of HIV/hepatitis C virus (HCV) testing

acceptance of sexually transmitted infections (STI) testing

+4 more

CHARIOT Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Comprehensive Tele-harm ReductionExperimental Treatment1 Intervention

Participants will have enhanced access to a physician and clinical psychologist via remote video technology wherever the participant is located and prefers engagement (SSP, home, shelter, encampment). Participants will be in this group for 12 months.

Group II: Off-site Linkage to HIV preventionActive Control1 Intervention

Participants in this group will receive off-site linkage to HIV care by having case management/social work services through our community engagement team. Participants will be in this group for 12 months.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of MiamiLead Sponsor

899 Previous Clinical Trials

409,382 Total Patients Enrolled

National Institute on Drug Abuse (NIDA)NIH

2,465 Previous Clinical Trials

2,618,283 Total Patients Enrolled

Hansel Tookes, MDPrincipal InvestigatorUniversity of Miami

1 Previous Clinical Trials

27 Total Patients Enrolled

Media Library

Comprehensive HIV and Harm Prevention Via Telehealth (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05897099 — N/A

Human Immunodeficiency Virus Infection Research Study Groups: Comprehensive Tele-harm Reduction, Off-site Linkage to HIV prevention

Human Immunodeficiency Virus Infection Clinical Trial 2023: Comprehensive HIV and Harm Prevention Via Telehealth Highlights & Side Effects. Trial Name: NCT05897099 — N/A

Comprehensive HIV and Harm Prevention Via Telehealth (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05897099 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still opportunities for participants to join this research effort?

"According to clinicaltrials.gov's records, this particular medical trial is not accepting new patients at the present time. The study was initially published in October 9th 2023 and last amended on June 1st 2023. Nevertheless, 464 alternate trials are currently seeking enrolments from volunteers."

Answered by AI

What key goals is this research attempting to achieve?

"During the period of up to 12 months, investigators in this trial will evaluate the efficacy of opioid use disorder medications in preventing HIV. Secondary objectives encompass syringe coverage (Number of syringes distributed/(number of injections per day x days between exchanges)), HCV cure (Negative HCV RNA viral load at least 12 weeks post treatment completion), and acceptance rate for STI testing (Receipt of test results for gonorrhea/chlamydia screening and syphilis screening)."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Comprehensive HIV and Harm Prevention Via Telehealth

Hansel Tookes 2024. "Comprehensive HIV and Harm Prevention Via Telehealth". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05897099.