CI Therapy for Stroke-related Arm Weakness
What You Need to Know Before You Apply
What is the purpose of this trial?
Constraint-Induced Therapy (CI Therapy) is a behavioral approach to neurorehabilitation and consists of multi-components that have been applied in a systematic method to improve the use of the limb or function addressed in the intensive treatment. CI Therapy for the more-affected upper extremity (UE) post-stroke is administered in daily treatment sessions over consecutive weekdays. Sessions include motor training with repeated, timed trials using a technique called shaping, a set of behavioral strategies known as the Transfer Package (TP) to improve the use of the more-affected hand in the life situation, and strategies to remind participants to use the more-affected UE including restraint. Robust improvements in the amount and qualify of use have been realized with stroke participants from mild-to-severe UE impairment.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is CI Therapy safe for humans?
How is CI Therapy for stroke-related arm weakness different from other treatments?
CI Therapy is unique because it involves intensive use of the affected arm by restricting the movement of the unaffected arm, which encourages the brain to reorganize and improve motor function. This approach is different from traditional therapies as it focuses on overcoming learned nonuse and promoting brain plasticity through repetitive practice.36789
What data supports the effectiveness of this treatment for stroke-related arm weakness?
Research shows that Constraint-Induced Movement Therapy (CI therapy) helps improve arm use in stroke patients by encouraging the use of the affected arm and promoting brain reorganization. This therapy has been effective in increasing the use of the affected arm in daily activities, with benefits lasting up to two years.368910
Who Is on the Research Team?
David Morris, PhD
Principal Investigator
University of Alabama at Birmingham
Are You a Good Fit for This Trial?
This trial is for adults who had a stroke at least 6 months ago and have mild difficulty using their upper limb. They must be able to move their wrist and fingers to some extent and score above a certain level on an activity log. People with severe cognitive impairment, unable to consent, or can't attend treatment sessions are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Grade 1 CI Therapy + Sensory Components administered over a two-week period
Follow-up
Participants are monitored for changes in mood and quality of life at 3 months post-treatment
What Are the Treatments Tested in This Trial?
Interventions
- Grade 1 CI Therapy +Sensory Components
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alabama at Birmingham
Lead Sponsor