Split-Belt Walking Training for Stroke

CP
BL
Overseen ByBeier Lin
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Stroke is a leading cause of long-term disability in adults. Although many individuals regain independent walking ability following stroke, nearly 50% experience persistent gait impairments characterized by asymmetrical walking patterns, slower walking speed, impaired balance, and increased fall risk. These persistent mobility limitations highlight the continued need for innovative rehabilitation strategies that improve gait function during stroke recovery. Split-belt treadmill walking (SBTW), in which each leg walks at a different belt speed, has demonstrated potential to improve step length symmetry in individuals with chronic stroke. However, the effects of SBTW during the subacute stage of stroke recovery, within the first 9 months post-stroke when neuroplasticity may be heightened, remain largely unknown. In addition, previous SBTW studies have not integrated active physiotherapist-led gait retraining into the intervention, despite physiotherapist-led gait rehabilitation representing standard clinical care following stroke. The purpose of this randomized controlled trial is to compare physiotherapist-led gait retraining using a traditional treadmill training protocol to physiotherapist-led gait retraining integrated with a split-belt treadmill training protocol during the first 9 months post-stroke. The study aims to examine the effectiveness of the use of split-belt treadmill training to augment physiotherapist-led gait retraining to improve between-leg gait symmetry and overground walking speed.

Are You a Good Fit for This Trial?

This trial is for adults who have had a stroke on one side of the brain within the past 9 months, causing weakness on one side. Participants must be able to walk at least ten meters (with or without aids), stand unsupported for five minutes, and speak English.

Inclusion Criteria

* less than 9 months post-stroke
* English speaking
I can stand on my own for at least five minutes.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo physiotherapist-led gait retraining using either split-belt or traditional treadmill training protocols

4 weeks
12 sessions (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • Split-belt walking training

Trial Overview

The study compares two types of physiotherapist-led treadmill walking training: traditional treadmill training versus split-belt treadmill training, where each leg walks at a different speed. The goal is to see which method better improves walking symmetry and speed after stroke.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Split-belt treadmill trainingExperimental Treatment1 Intervention
Group II: Traditional treadmill trainingActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of British Columbia

Lead Sponsor

Trials
1,506
Recruited
2,528,000+