Acceptance and Commitment Therapy for PTSD and Alcohol Use Disorder
(ACT-SHARE Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your healthcare provider.
What data supports the effectiveness of the treatment ACT-SHARE for PTSD and Alcohol Use Disorder?
Research shows that Acceptance and Commitment Therapy (ACT) can help reduce PTSD symptoms and alcohol use in veterans, with improvements in quality of life and fewer depressive symptoms. ACT has also been shown to enhance treatment outcomes for alcohol use disorder when combined with usual care, leading to better drinking and mental health outcomes.12345
Is Acceptance and Commitment Therapy (ACT) safe for treating PTSD and Alcohol Use Disorder?
ACT has been studied in various conditions, including PTSD and alcohol use disorder, and is generally considered safe. In studies, participants have shown improvements in symptoms and quality of life, with high retention rates, indicating that people tend to stick with the treatment without major safety concerns.13678
How does the treatment ACT-SHARE differ from other treatments for PTSD and Alcohol Use Disorder?
ACT-SHARE is unique because it combines mindfulness and acceptance strategies to help patients with PTSD and Alcohol Use Disorder, focusing on reducing avoidance and increasing psychological flexibility. Unlike traditional therapies, it emphasizes values-based behavior and frequent mindfulness practice, which may lead to sustained improvements in symptoms and quality of life.137910
What is the purpose of this trial?
Veterans seeking to improve their romantic relationships when high conflict and unhealthy dynamics (e.g., aggression) are present remain underserved within the VHA with few treatment options. Veterans with PTSD and alcohol misuse face compounding and overlapping barriers to intimate relationship functioning warranting tailored interventions. These Veterans may be best served through individual, Acceptance and Commitment Therapy (ACT) interventions which can both 1) improve the ability to manage challenging, internal experiences (e.g., physiological reactivity, cravings, beliefs about worth and trust) and 2) encourage participation in valued actions to improve relationship functioning. Following development and refinement, this clinical trial will pilot an evidence-based, integrated ACT intervention (ACT for Social Health, Achievement, and Relationship Effectiveness \[ACT-SHARE\]) to improve relationship health and safety for Veterans with PTSD alcohol misuse.
Research Team
Hannah Grigorian, PhD
Principal Investigator
VA Bedford HealthCare System, Bedford, MA
Eligibility Criteria
This trial is for Veterans over 18 with PTSD and alcohol misuse who have experienced intimate partner violence (IPV) recently. They should want to improve their romantic relationships, be able to give informed consent, and agree to audio recordings. It's not for those needing inpatient care for suicidality, detoxification from severe substance use, or those with cognitive impairments or active psychosis/mania.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Intervention Development
Development and refinement of the ACT-SHARE intervention through iterative feedback
Treatment
Participants receive the ACT-SHARE intervention, which includes Acceptance and Commitment Therapy tailored for social health, achievement, and relationship effectiveness
Follow-up
Participants are monitored for changes in relationship functioning, IPV use, PTSD symptoms, and alcohol use
Treatment Details
Interventions
- ACT-SHARE
Find a Clinic Near You
Who Is Running the Clinical Trial?
VA Office of Research and Development
Lead Sponsor