Exercise for Post-Traumatic Stress Disorder
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this clinical trial is to test how exercise affects learning and memory processes relevant to the treatment of PTSD. Participants will complete a baseline intake followed by two experimental sessions. During the first experimental session, participants will undergo an MRI session of imaginal exposure to traumatic memory cues followed by 30-minutes of moderate intensity exercise or low intensity exercise. Participants will complete a second session of imaginal exposure with MRI 24 hours later.
Will I have to stop taking my current medications?
The trial requires that you do not have recent changes in psychiatric medication within the past 4 weeks, and you must be able to abstain from daily benzodiazepine or stimulant use during study sessions.
Is exercise safe for people with PTSD?
How does exercise treatment for PTSD differ from other treatments?
Exercise treatment for PTSD is unique because it uses physical activity to reduce symptoms, potentially through mechanisms like improving brain function and reducing inflammation, unlike traditional treatments that often rely on medication or talk therapy. It can also improve related conditions like anxiety and depression, making it a versatile and accessible option for many individuals.12356
What data supports the effectiveness of the treatment Low Intensity Exercise, Low-Intensity Exercise, Light Exercise, Mild Exercise, Moderate Intensity Exercise, Aerobic Exercise, Physical Activity, Moderate Exercise for PTSD?
Who Is on the Research Team?
Thomas G Adams, Jr., PhD
Principal Investigator
University of Kentucky
Christal Badour, PhD
Principal Investigator
University of Kentucky
Are You a Good Fit for This Trial?
This trial is for adults with PTSD from interpersonal violence. It explores how different exercise intensities affect learning and memory tied to PTSD treatment.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline and Experimental Sessions
Participants complete baseline intake and two experimental sessions involving imaginal exposure and exercise
Follow-up
Participants are monitored for changes in heart rate, BOLD response, and subjective emotional ratings
What Are the Treatments Tested in This Trial?
Interventions
- Low Intensity Exercise
- Moderate Intensity Exercise
Find a Clinic Near You
Who Is Running the Clinical Trial?
Christal L Badour
Lead Sponsor
Thomas Adams
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator
University of Texas at Austin
Collaborator