Anthocyanin-rich Extracts for Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to compare the effects of anthocyanin-rich extracts from berries and flowers on the immune system to those of a placebo. Participants will take various combinations of these extracts over several weeks to determine which offers the most benefit. Healthy adults with easily visible veins who can adhere to the study's guidelines may qualify. As an unphased study, this trial provides a unique opportunity to contribute to scientific understanding and potentially improve health outcomes.
Will I have to stop taking my current medications?
The trial does not specify if you must stop taking your current medications, but it does exclude people taking certain medications like anti-inflammatory drugs and some mental health prescriptions. Other medications will be evaluated individually, so it's best to discuss your specific situation with the trial team.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research shows that extracts rich in anthocyanins, such as those from berries, are generally safe for people. These berry extracts possess antioxidant properties, helping to protect cells from damage.
For extracts from flowers and leaves high in anthocyanins, research indicates they are safe and may have cancer-fighting properties. Studies have used these extracts without reporting serious side effects.
The combination of berry and leaf extracts also appears safe for people. Studies suggest it offers antioxidant benefits, potentially protecting against some cancers. No major safety concerns have been reported for this blend.
Overall, these anthocyanin-rich extracts are considered safe, with research noting no major adverse effects. However, since individual reactions can vary, consulting a healthcare provider is important if there are any concerns.12345Why are researchers excited about this trial's treatments?
Researchers are excited about these treatments because they use anthocyanin-rich extracts, which are natural compounds found in berries, flowers, and leaves. Unlike traditional cancer treatments like chemotherapy and radiation, which can have severe side effects, these extracts are derived from natural sources and may offer a gentler approach to treatment. Anthocyanins have powerful antioxidant properties, which might help fight cancer by reducing inflammation and preventing cell damage. This novel approach targets cancer differently, potentially offering a new, less invasive option for patients.
What evidence suggests that this trial's treatments could be effective for cancer?
This trial will evaluate the effects of different anthocyanin-rich extracts on cancer. Research has shown that berry extracts rich in anthocyanins might interfere with cancer treatments and offer limited protection for healthy cells. Some studies suggest these extracts can reduce DNA damage and increase antioxidants, which help protect the body. Participants in this trial will receive either an anthocyanin-rich berry extract, a flower/leaf extract, or a berry/leaf blend. Extracts from flowers and leaves rich in anthocyanins have shown potential in fighting cancer by slowing cancer cell growth and promoting their death, making them promising for preventing and treating cancer. A blend of berry and leaf extracts showed promise in stopping tumor growth in animal studies and may enhance the effectiveness of current cancer treatments. Overall, these natural extracts have demonstrated potential in fighting cancer by protecting healthy cells and targeting cancer cells.26789
Are You a Good Fit for This Trial?
This trial is for healthy adults aged 18-75 who have visible veins for blood draws. Participants must skip exercise and supplements on the morning of a visit, avoid caffeine an hour before, maintain a consistent diet and lifestyle, eat bland breakfasts on clinic days, and refrain from music, candy, gum, or device use during visits.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants consume a test product on each of the four clinic days, with a 1-week wash-out period between each product
Follow-up
Participants are monitored for changes in stem cell numbers in blood circulation
What Are the Treatments Tested in This Trial?
Interventions
- Anthocyanin-rich berry extract
- Anthocyanin-rich flower/leaf extract
- Berry/leaf blend
Trial Overview
The study is testing the immediate immune effects of three nutraceutical ingredients: anthocyanin-rich berry extract, flower/leaf extract, and their blend compared to a placebo. The goal is to understand how these natural substances affect stem cell surveillance in the body.
How Is the Trial Designed?
4
Treatment groups
Experimental Treatment
Participants consume a test product on each of the four clinic days, at least 1 week apart, allowing for 1 week wash-out period between each product. Participants will consume each of the 3 active test products versus placebo over 5 weeks, in this order: D, A, B, C.
Participants consume a test product on each of the four clinic days, at least 1 week apart, allowing for 1 week wash-out period between each product. Participants will consume each of the 3 active test products versus placebo over 5 weeks, in this order: C, D. A, B.
Participants consume a test product on each of the four clinic days, at least 1 week apart, allowing for 1 week wash-out period between each product. Participants will consume each of the 3 active test products versus placebo over 5 weeks, in this order: B, C, D, A.
Participants consume a test product on each of the four clinic days, at least 1 week apart, allowing for 1 week wash-out period between each product. Participants will consume each of the 3 active test products versus placebo over 5 weeks, in this order: A, B, C, D.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Natural Immune Systems Inc
Lead Sponsor
Citations
Effects of anthocyanins on the prevention and treatment of ...
DNA oxidative damage decreased in human subjects who had drunk a juice rich in anthocyanins and showed significant increases in reduced glutathione, compared ...
P12-22 Anthocyanin-rich elderberry extract during ...
This study assessed the potential of anthocyanin-rich elderberry extracts to reduce irinotecan-induced damage on the intestinal tissue without compromising its ...
Anthocyanin-Rich Berry Extracts Affect SN-38-Induced ...
The herein reported data argue towards an interference of anthocyanins with successful treatment of cancer cells and a lack of protective properties in healthy ...
Anthocyanins: From Natural Colorants to Potent Anticancer ...
The anticancer potential of anthocyanins was evaluated against human colorectal cancer cells (SW480 and SW620) by providing 10%–40% (v/v) of ...
Systematic Review and Meta-Analysis of 44 Randomized ...
Conclusion: Habitual intake of anthocyanins and anthocyanin-rich berries could protect against CVDs possibly via improving blood lipid profiles ...
Anthocyanin-Rich Berry Extracts Affect SN-38-Induced ...
The herein reported data argue towards an interference of anthocyanins with successful treatment of cancer cells and a lack of protective ...
Safety and whole-body antioxidant potential of a novel ...
Edible berry extracts rich in anthocyanins possess a broad spectrum of therapeutic, pharmacologic and anti-carcinogenic properties. Six berry extracts (wild ...
Anthocyanin-rich Mulberry extract inhibit the gastric cancer ...
This study revealed that the extracts of Mulberry, MACs, inhibited the growth of human gastric carcinoma cells.
In Vitro Inhibitory Potential of Different Anthocyanin-Rich ...
Hence, while BB does not per se protect the cancer cells from SN-38-induced damage, the measured combined effect is lower than the theoretically ...
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