60 Participants Needed

Sex Differences in Neurocirculatory Control for Obstructive Sleep Apnea

JB
IG
Overseen ByIan Greenlund, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to explore how men and women might differ in controlling blood pressure when they have untreated obstructive sleep apnea (OSA), a condition that affects breathing during sleep. Understanding these differences could lead to better treatments for managing blood pressure in people with OSA. Individuals with untreated OSA, who have no other sleep disorders and no major health issues like heart disease or diabetes, might be suitable candidates for this study. As an unphased trial, this study offers participants the opportunity to contribute to groundbreaking research that could enhance future treatments for OSA-related blood pressure issues.

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to uncover how men and women might differ in their neurocirculatory control, which is how our nervous system manages blood flow and pressure. Unlike typical studies that focus on a one-size-fits-all treatment approach, this trial could pave the way for personalized healthcare solutions, tailoring treatments based on sex-specific physiological differences. This could lead to more effective and targeted interventions for conditions related to blood pressure and circulatory health, offering improved outcomes for everyone.

Who Is on the Research Team?

JB

Joshua Bock, PhD

Principal Investigator

Mayo Clinic

Are You a Good Fit for This Trial?

Inclusion Criteria

I am between 20 and 70 years old.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline Assessment

Baseline measurements of blood pressure, arterial stiffness, endothelial function, and sympathetic nerve activity are conducted

1 week
1 visit (in-person)

Follow-up

Participants are monitored for any changes in neurocirculatory control and safety after baseline assessments

4 weeks

What Are the Treatments Tested in This Trial?

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials
3,427
Recruited
3,221,000+

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Collaborator

Trials
508
Recruited
1,090,000+
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