L-arginine for Human Performance

Overseen By Mikal Thrones, BSc

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: University of Manitoba

Must not be taking: Any medication

Disqualifiers: Smokers, Cardiovascular, Metabolic, others

Compensation: Varies

Number of Visits: 2

Duration: 2 weeks

20 Participants Needed

Trial Summary

What is the purpose of this trial?

The purpose of this study is to evaluate if acute ingestion of L-arginine will enhance anaerobic exercise performance in young, healthy, and recreationally active adults.

Eligibility Criteria

This trial is for young adults aged 18-39 who are healthy and moderately active, exercising at least an hour a day, three days a week for the past month. Smokers or those with heart, metabolic, nerve diseases or mental health issues can't join. Also excluded are people on medication or allergic to L-arginine or dextrose.

Inclusion Criteria

Recreationally physically active individuals performing 1-hour of exercise per day over 3 days per week for a minimum of 1 month

Exclusion Criteria

Smokers

I have a heart, metabolic, brain, or mental health condition.

I am currently taking medication for a health condition.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants complete two exercise sessions after ingesting either a placebo or L-arginine, with a one-week wash-out period between sessions

2 weeks

2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 week

Treatment Details

Interventions

• L-arginine

Trial Overview The study tests whether taking L-arginine improves anaerobic exercise performance compared to a placebo (dextrose). Participants will be given either L-arginine or placebo in a controlled environment to measure any changes in their physical output.

Participant Groups

Group I: L-arginine Experimental Treatment 1 Intervention

Participants will ingest 2 grams of L-arginine before completing three anaerobic exercise tasks (grip strength, vertical jump, and Wingate cycle ergometer test).

Group II: Placebo Placebo Group 1 Intervention

Participants will ingest 2 grams of placebo (dextrose) before completing three anaerobic exercise tasks (grip strength, vertical jump, and Wingate cycle ergometer test).

Who Is Running the Clinical Trial?

University of Manitoba

Lead Sponsor

Trials

628

Recruited

209,000+