L-arginine for Human Performance
SM
MT
Overseen ByMikal Thrones, BSc
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: University of Manitoba
Trial Summary
What is the purpose of this trial?
The purpose of this study is to evaluate if acute ingestion of L-arginine will enhance anaerobic exercise performance in young, healthy, and recreationally active adults.
Eligibility Criteria
This trial is for young adults aged 18-39 who are healthy and moderately active, exercising at least an hour a day, three days a week for the past month. Smokers or those with heart, metabolic, nerve diseases or mental health issues can't join. Also excluded are people on medication or allergic to L-arginine or dextrose.Inclusion Criteria
Recreationally physically active individuals performing 1-hour of exercise per day over 3 days per week for a minimum of 1 month
Exclusion Criteria
Smokers
I have a heart, metabolic, brain, or mental health condition.
I am currently taking medication for a health condition.
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Timeline
Screening
Participants are screened for eligibility to participate in the trial
1-2 weeks
Treatment
Participants complete two exercise sessions after ingesting either a placebo or L-arginine, with a one-week wash-out period between sessions
2 weeks
2 visits (in-person)
Follow-up
Participants are monitored for safety and effectiveness after treatment
1 week
Treatment Details
Interventions
- L-arginine
Trial Overview The study tests whether taking L-arginine improves anaerobic exercise performance compared to a placebo (dextrose). Participants will be given either L-arginine or placebo in a controlled environment to measure any changes in their physical output.
Participant Groups
2Treatment groups
Experimental Treatment
Placebo Group
Group I: L-arginineExperimental Treatment1 Intervention
Participants will ingest 2 grams of L-arginine before completing three anaerobic exercise tasks (grip strength, vertical jump, and Wingate cycle ergometer test).
Group II: PlaceboPlacebo Group1 Intervention
Participants will ingest 2 grams of placebo (dextrose) before completing three anaerobic exercise tasks (grip strength, vertical jump, and Wingate cycle ergometer test).
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Who Is Running the Clinical Trial?
University of Manitoba
Lead Sponsor
Trials
628
Recruited
209,000+
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