20 Participants Needed

L-arginine for Human Performance

SM
MT
Overseen ByMikal Thrones, BSc
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: University of Manitoba

Trial Summary

What is the purpose of this trial?

The purpose of this study is to evaluate if acute ingestion of L-arginine will enhance anaerobic exercise performance in young, healthy, and recreationally active adults.

Eligibility Criteria

This trial is for young adults aged 18-39 who are healthy and moderately active, exercising at least an hour a day, three days a week for the past month. Smokers or those with heart, metabolic, nerve diseases or mental health issues can't join. Also excluded are people on medication or allergic to L-arginine or dextrose.

Inclusion Criteria

Recreationally physically active individuals performing 1-hour of exercise per day over 3 days per week for a minimum of 1 month

Exclusion Criteria

Smokers
I have a heart, metabolic, brain, or mental health condition.
I am currently taking medication for a health condition.
See 1 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants complete two exercise sessions after ingesting either a placebo or L-arginine, with a one-week wash-out period between sessions

2 weeks
2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 week

Treatment Details

Interventions

  • L-arginine
Trial Overview The study tests whether taking L-arginine improves anaerobic exercise performance compared to a placebo (dextrose). Participants will be given either L-arginine or placebo in a controlled environment to measure any changes in their physical output.
Participant Groups
2Treatment groups
Experimental Treatment
Placebo Group
Group I: L-arginineExperimental Treatment1 Intervention
Participants will ingest 2 grams of L-arginine before completing three anaerobic exercise tasks (grip strength, vertical jump, and Wingate cycle ergometer test).
Group II: PlaceboPlacebo Group1 Intervention
Participants will ingest 2 grams of placebo (dextrose) before completing three anaerobic exercise tasks (grip strength, vertical jump, and Wingate cycle ergometer test).

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Who Is Running the Clinical Trial?

University of Manitoba

Lead Sponsor

Trials
628
Recruited
209,000+
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