Green bean puree for Short Bowel Syndrome

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Short Bowel SyndromeGreen bean puree - DietarySupplement
Eligibility
4 - 18
All Sexes
What conditions do you have?
Select

Study Summary

This trial will help researchers understand if dietary fiber is a safe and effective treatment for short bowel syndrome.

Eligible Conditions
  • Short Bowel Syndrome

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: 3 weeks-6 months

3 weeks-6 months
Microbiome/Metabolome Changes
Symptoms

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Control Arm -
1 of 2
Short Bowel Syndrome Arm
1 of 2

Active Control

Experimental Treatment

60 Total Participants · 2 Treatment Groups

Primary Treatment: Green bean puree · No Placebo Group · N/A

Short Bowel Syndrome Arm
DietarySupplement
Experimental Group · 1 Intervention: Green bean puree · Intervention Types: DietarySupplement
Control Arm -
DietarySupplement
ActiveComparator Group · 1 Intervention: Green bean puree · Intervention Types: DietarySupplement

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3 weeks-6 months

Who is running the clinical trial?

University of PennsylvaniaOTHER
1,840 Previous Clinical Trials
41,126,322 Total Patients Enrolled
Children's Hospital of PhiladelphiaLead Sponsor
649 Previous Clinical Trials
7,849,429 Total Patients Enrolled
2 Trials studying Short Bowel Syndrome
16 Patients Enrolled for Short Bowel Syndrome
Wenjing Zong, MDPrincipal InvestigatorChildren's Hospital of Philadelphia
Christina Bales, MDPrincipal InvestigatorChildren's Hospital of Philadelphia
Lindsey Albenberg, DOStudy DirectorChildren's Hospital of Philadelphia
3 Previous Clinical Trials
23 Total Patients Enrolled

Eligibility Criteria

Age 4 - 18 · All Participants · 9 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
At least 20% of calories from oral food must be from food that does not contain fiber.
You have a history of short bowel syndrome based on surgical/imaging records
You have no or negligible amount of fiber in your diet.
At least 20% of calories from formula taken orally or via tube.
Antibiotic use is allowed, however, should be on a stable regimen of antibiotics starting from 2 weeks prior to intervention until end of study or end of week 3 whichever is sooner.
Previous history of fiber introduction failure is acceptable as long as clinically stable at the time of recruitment.
Fiber supplementation is appropriate per primary physician.