5000 Participants Needed

Biosample Repository for Tuberous Sclerosis Complex

Recruiting at 26 trial locations
GR
EC
AA
Overseen ByAyat Abi
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: National Tuberous Sclerosis Association
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial collects blood, DNA, and tissue samples from individuals with tuberous sclerosis complex (TSC) or sporadic lymphangioleiomyomatosis (LAM). The goal is to create a repository that aids researchers in studying how these conditions affect health over a lifetime. Participants' samples link to a database that tracks their health history to understand the long-term impact of these diseases. Individuals diagnosed with TSC or LAM might be suitable candidates. As an unphased study, this trial offers participants the chance to contribute to valuable research that could enhance understanding and treatment of these conditions.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications.

Why are researchers excited about this trial?

Researchers are excited about the TSC Biosample Repository and Natural History Database because it offers a unique approach to understanding tuberous sclerosis complex (TSC). Unlike traditional treatments that focus solely on managing symptoms, this initiative collects detailed biosamples and clinical data to map out the natural history of TSC over time. This comprehensive database could lead to breakthroughs in personalized medicine, helping doctors predict how the disease might progress in individual patients and tailor treatments accordingly. By creating a more complete picture of TSC, this project has the potential to drive the development of more effective therapies in the future.

Who Is on the Research Team?

SR

Steve Roberds, PhD

Principal Investigator

TSC Alliance

Are You a Good Fit for This Trial?

Inclusion Criteria

Diagnosis of tuberous sclerosis complex or lymphangioleiomyomatosis (sporadic LAM).

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

Biosample Collection

Collection of blood, tissues, and cells from individuals with TSC at various locations including clinical study sites, participant's homes, or educational meetings

Ongoing

Data Collection

Collection of retrospective and prospective clinical data on individuals with TSC over their lifespan

Average 15 years

Follow-up

Participants are monitored for the impact of TSC on their health over their lifetime

Ongoing

What Are the Treatments Tested in This Trial?

Interventions

  • TSC Biosample Repository
  • TSC Natural History Database

Find a Clinic Near You

Who Is Running the Clinical Trial?

National Tuberous Sclerosis Association

Lead Sponsor

Trials
1
Recruited
5,000+
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