Origin Satiety Complex for Hunger and Satiety
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new product, Origin Satiety Complex, to evaluate its effectiveness in managing hunger and fullness in healthy adults. Researchers aim to determine if this product alters feelings of hunger or fullness compared to a placebo. The treatment includes ingredients such as L-glutamine, fiber, and various plant extracts. Individuals who are generally healthy, have a BMI between 18.5 and 29.9, and can maintain their current lifestyle during the study may be suitable candidates. As an unphased trial, this study provides a unique opportunity to contribute to scientific understanding and potentially gain new insights into managing hunger and fullness.
Is there any evidence suggesting that the Origin Satiety Complex is likely to be safe for humans?
Research on the safety of the Origin Satiety Complex remains in the early stages, so data is limited. However, the ingredients—such as L-glutamine, fiber, spinach, sweet potato, blueberry, green coffee bean, cinnamon, and probiotics—are generally considered safe. These components are commonly found in many dietary supplements and everyday foods.
Although specific studies on the entire complex are lacking, the individual ingredients typically do not cause serious side effects when used correctly. As this combination is new, the trial is in a phase called "Not Applicable," focusing on initial safety and effectiveness. This phase usually indicates that the treatment has not undergone extensive safety testing yet.
Prospective participants should consult a doctor to understand the possible risks and benefits.12345Why are researchers excited about this trial?
Origin Satiety Complex is unique because it combines a variety of natural ingredients like L-glutamine, fiber, spinach extract, and sweet potato powder to potentially control hunger and enhance satiety. Unlike typical appetite suppressants that often rely on a single active ingredient or chemical compound, this complex uses a multi-faceted approach with natural extracts and probiotics. Researchers are particularly excited about the inclusion of green coffee bean and cinnamon bark extracts, which are thought to help regulate blood sugar and metabolism, offering a fresh angle on managing hunger and fullness compared to existing options.
What evidence suggests that the Origin Satiety Complex is effective for hunger and satiety?
Research shows that the Origin Satiety Complex, which participants in this trial may receive, might help control hunger and increase feelings of fullness. This product includes ingredients such as L-glutamine, fiber, and various plant extracts, which are believed to enhance satiety. Studies indicate that fiber and certain plant extracts can slow digestion, prolonging the feeling of fullness. Additionally, ingredients like green coffee bean extract have been linked to appetite control. By targeting these effects, the Origin Satiety Complex aims to reduce hunger and increase satisfaction after eating.678910
Who Is on the Research Team?
David Crowley, MD
Principal Investigator
KGK Science Inc.
Are You a Good Fit for This Trial?
This trial is for healthy adults interested in testing a new product, Origin Satiety Complex, designed to affect feelings of fullness and hunger. Specific eligibility criteria are not provided but typically include age range, general health status, and no current use of conflicting medications or supplements.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive the investigational product (IP) or placebo and are assessed for hunger and satiety using the Eating Behavior Visual Analog Scales (VAS)
Follow-up
Participants are monitored for post-emergent adverse events and changes in blood pressure and heart rate after supplementation
What Are the Treatments Tested in This Trial?
Interventions
- Origin Satiety Complex
Trial Overview
The study tests the Origin Satiety Complex against a placebo to see if it changes how hungry or full participants feel after eating. It measures this using visual scales over about half a day.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Origin Satiety Complex consists of a mix of L-glutamine, fiber blend, spinach whole herb extract, sweet potato powder, blueberry fruit extract, green coffee bean extract, cinnamon bark extract, and a probiotic blend.
Placebo consists of a commercially available juice powder, Tang.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Vora Life LLC
Lead Sponsor
KGK Science Inc.
Industry Sponsor
Najla Guthrie
KGK Science Inc.
Chief Executive Officer since 1997
Research career at the Centre for Human Nutrition, University of Western Ontario
Dr. Bibiane Zakaria
KGK Science Inc.
Chief Medical Officer since 2023
MD from an unspecified institution
Citations
Hunger and Satiety Mechanisms and Their Potential ... - PMC
This review describes selected recent research from Full4Health and how new mechanistic findings could be exploited to adapt and control our physiological ...
Does hunger and satiety drive eating anymore? Increasing ...
The main outcomes of interest included the number and size (energy/d) of meal and snack EOs, the composition (food or beverage) of each EO, and the time ...
Successful Development of Satiety Enhancing Food Products
This paper aims to present the contours of such an integrative approach by going through the current state of the art around satiety enhancing foods.
Hunger, Satiety, and Their Vulnerabilities
The psychological states of hunger and satiety play an important role in regulating human food intake.
Satiation, satiety and their effects on eating behaviour
1. Introduction 2. Physiological mechanisms of satiation and satiety 3. Measuring satiation and satiety 4. The effects of foods and drinks on satiety
A Clinical Trial to Determine the Safety and Efficacy of ...
A Clinical Trial to Determine the Safety and Efficacy of an Origin Satiety Complex on Self-reported Hunger and Satiety in Healthy Adults.
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ctv.veeva.com
ctv.veeva.com/study/a-clinical-trial-to-determine-the-safety-and-efficacy-of-an-origin-satiety-complex-on-self-reportedA Clinical Trial to Determine the Safety and Efficacy of an ...
A Clinical Trial to Determine the Safety and Efficacy of an Origin Satiety Complex on Self-reported Hunger and Satiety in Healthy Adults.
Hunger, Satiety, and Their Vulnerabilities - PMC - NIH
The psychological states of hunger and satiety play an important role in regulating human food intake.
Satiety and food availability modulate the approach and ...
These findings suggest that food availability plays a crucial role in shaping both motivational and inhibitory control processes.
Hunger and Satiety Peptides: Is There a Pattern to Classify ...
Cluster analysis could be a good tool to distinguish and characterize the differences in hormone responses between PWS and obese or healthy controls.
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