Cold Water Immersion for Immune Function

Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: University of Northern Colorado
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines how cold water immersion might boost the immune system, improve sleep and mental health, and build muscle strength. It compares two types of cold exposure: cold tubs and cold showers. Participants will try one of these methods or join a group that does not engage in cold water activities. Individuals with no more than three cold water sessions in the past month and without specific chronic conditions like heart disease or diabetes may be eligible to join. As an unphased trial, this study offers a unique opportunity to explore potential health benefits from cold water exposure.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but it excludes people who use anti-inflammatory medication regularly. If you take these medications often, you might not be eligible to participate.

What prior data suggests that cold water immersion is safe for improving immune function and well-being?

Research shows that cold water immersion (CWI), such as using cold tubs or taking cold showers, can affect health in various ways. Some studies suggest that CWI might help reduce inflammation, improve mood, and positively impact stress, immunity, and sleep quality. These benefits typically appear over time with regular practice.

However, risks exist. The National Center for Cold Water Safety warns that sudden immersion in very cold water, especially below 60°F (15.5°C), can be dangerous and even life-threatening if not done carefully.

While many people tolerate cold water exposure well, caution is essential, particularly for newcomers. Always monitor how the body feels and start slowly to avoid negative effects.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores how simple, non-pharmaceutical methods like cold water immersion might boost immune function. Unlike traditional immune support treatments, which often involve medications or supplements, this trial looks at physical techniques—either cold showers or cold tub immersions—as a way to potentially enhance the body's natural defenses. This approach could provide a natural, cost-effective alternative to current immune-boosting strategies, with the added benefit of being accessible and having minimal side effects.

What evidence suggests that cold water immersion could be effective for improving immune function and well-being?

This trial will compare the effects of cold water immersion through cold showers and cold tub immersion on immune function. Research has shown that cold water exposure, such as in cold tubs or showers, can boost the immune system and improve overall health. Studies suggest that regular cold water immersion can reduce inflammation and stress while strengthening the immune system by increasing certain immune cells and antibodies. Cold showers and tubs might also improve sleep and mental health. Both methods could enhance quality of life, and cold tubs may aid in muscle recovery after exercise. While more research is needed for definitive proof, current evidence is promising.12367

Are You a Good Fit for This Trial?

This trial is for individuals who want to explore how cold water immersion (CWI) might affect their immune system, muscle strength, sleep quality, and mental health. Participants will either take cold showers or baths three times a week for four weeks. People with certain health conditions that could be worsened by cold exposure are not eligible.

Exclusion Criteria

Currently practices CWI for more than 3 times in the last month
Pregnant or planning to become pregnant
I regularly take anti-inflammatory medication.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo 4 weeks of Cold Tub or Cold Shower interventions at a frequency of 3 times a week for 4 minutes

4 weeks
12 sessions (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Cold Water Immersion (CWI) - Cold Shower (CS)
  • Cold Water Immersion (CWI) - Cold Tub Immersion (CI)
Trial Overview The study tests if regular cold showers or tub immersions over four weeks can boost the immune system and improve well-being, sleep quality, muscular strength compared to those who do not undergo CWI. It also examines differences between the effects of cold showers versus tubs.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Group I: Control Group (CO)Experimental Treatment1 Intervention
Group II: Cold Tub Immersion Group (CI)Experimental Treatment1 Intervention
Group III: Cold Shower Group (CS)Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Northern Colorado

Lead Sponsor

Trials
8
Recruited
550+

Published Research Related to This Trial

Cold water immersion (CWI) at temperatures of 10-15°C for 5-15 minutes is shown to effectively enhance recovery of performance in athletes, making it a popular choice for minimizing fatigue after exercise.
Contrast water therapy (CWT), which alternates between cold and hot water, may also aid recovery, but its effectiveness depends on equal time spent in both temperatures and short immersion durations, with no clear dose-response relationship established.
Water immersion recovery for athletes: effect on exercise performance and practical recommendations.Versey, NG., Halson, SL., Dawson, BT.[2022]

Citations

1.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/39879231/
Effects of cold-water immersion on health and wellbeingThis systematic review suggests that CWI delivers time-dependent effects on inflammation, stress, immunity, sleep quality, and quality of life.
Regular cold shower exposure modulates humoral and cell ...Regular cold shower exposure appears to enhance humoral and cell-mediated immunity through the upregulation of antibodies, interleukin-2, and interleukin-4.
Effects of cold-water immersion on health and wellbeingThis systematic review suggests that CWI delivers time-dependent effects on inflammation, stress, immunity, sleep quality, and quality of life.
Health effects of voluntary exposure to cold waterFor example, in the popular literature it has been claimed that it can boost the immune system, treat depression, enhance peripheral circulation ...
Can taking a cold plunge after your workout be beneficial?Research indicates that icy water may have a positive effect on recovery after exercise by reducing inflammation and soreness.
You're not a polar bear: The plunge into cold water comes ...The National Center for Cold Water Safety warns that sudden immersion in water under 60 degrees Fahrenheit can kill a person in less than a ...
Ice bath benefits, risks, and safety explainedNational Center for Cold Water Safety, sudden immersion in water colder than 60°F (15.5°C) can kill a person in less than 1 minute. Research ...
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security