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Vertical Positioning for Respiratory Failure

N/A
Waitlist Available
Led By John P Kress, MD
Research Sponsored by University of Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients aged ≥18 years who are mechanically ventilated
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline to 1hr
Awards & highlights

Study Summary

This trial will help researchers learn if changing from lying down to sitting up affects how well oxygen moves from the lungs into the blood for people with hypoxemic respiratory failure.

Who is the study for?
This trial is for adults over 18 who are on mechanical ventilation due to respiratory failure, with specific oxygen levels in their blood. It's not for those with severe heart rates, low blood pressure, gastrointestinal bleeding, high intracranial pressure, pregnancy, or if they weren't walking before hospitalization.Check my eligibility
What is being tested?
The study examines the impact of moving from lying down to standing up on breathing and oxygen levels in patients with hypoxemic respiratory failure. Researchers want to see if this change improves how well lungs transfer oxygen into the blood.See study design
What are the potential side effects?
Since the intervention involves changing position from supine to upright, potential side effects may include discomfort or dizziness due to movement but will largely depend on each patient's condition.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 18 or older and am on a mechanical ventilator.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline to 1hr
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline to 1hr for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
PaO2 to FiO2 ratio
Secondary outcome measures
Change in blood pH
Oxygen Saturation
change in blood PCO2
Other outcome measures
Tidal Volume
Vital Signs

Trial Design

1Treatment groups
Experimental Treatment
Group I: Mechanically VentilatedExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

University of ChicagoLead Sponsor
1,004 Previous Clinical Trials
819,761 Total Patients Enrolled
5 Trials studying Respiratory Failure
30,732 Patients Enrolled for Respiratory Failure
John P Kress, MDPrincipal InvestigatorUniversity of Chicago
8 Previous Clinical Trials
2,134 Total Patients Enrolled
1 Trials studying Respiratory Failure
200 Patients Enrolled for Respiratory Failure

Media Library

Standing Clinical Trial Eligibility Overview. Trial Name: NCT01705119 — N/A
Respiratory Failure Research Study Groups: Mechanically Ventilated
Respiratory Failure Clinical Trial 2023: Standing Highlights & Side Effects. Trial Name: NCT01705119 — N/A
Standing 2023 Treatment Timeline for Medical Study. Trial Name: NCT01705119 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
The Effects of Vertical Position on Gas Exchange in Patients With Respiratory Failure
2012. "The Effects of Vertical Position on Gas Exchange in Patients With Respiratory Failure". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01705119.
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~1 spots leftby Apr 2025
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