Resistant Starch for Chronic Kidney Disease
(ReSPECKD Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests if taking Resistant Potato Starch (RPS) can help patients with Chronic Kidney Disease by improving their gut bacteria and reducing harmful blood toxins. A high resistant starch diet has shown to slow down CKD progression and reduce oxidative stress and inflammation in rats.
Who Is on the Research Team?
Dylan Mackay, PhD
Principal Investigator
University of Manitoba
Are You a Good Fit for This Trial?
Adults over 18 with Chronic Kidney Disease (CKD) and an eGFR <15 mL/min/1.73m^2, who can read English and consent to study requirements. Women must use birth control if of child-bearing potential. Excludes those with uncontrolled diabetes (A1C > 10%), cognitive impairments, allergies to potatoes or corn, severe gastrointestinal conditions, severe anemia, recent antibiotic use, or on dialysis.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Run-in
Participants receive corn starch for acclimatization
Treatment Period 1
Participants receive either RPS or corn starch based on randomization
Washout
Participants consume corn starch to clear previous treatment effects
Treatment Period 2
Participants receive the treatment not previously consumed
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Resistant Potato Starch
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Manitoba
Lead Sponsor