Fat Grafting for Breast Reconstruction
Trial Summary
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Fat Grafting for Breast Reconstruction?
Research shows that fat grafting can effectively improve breast appearance after reconstruction, correct deformities, and enhance skin thickness, especially when combined with techniques like pre-expansion with BRAVA. It is also noted for creating a natural look and improving tissue quality in radiated areas.12345
How is fat grafting different from other breast reconstruction treatments?
Fat grafting for breast reconstruction is unique because it uses the patient's own fat, harvested from other parts of the body, to rebuild the breast. This method can be used alone or in combination with other techniques, and it avoids the use of implants, making it a more natural option for some patients. It is particularly suitable for those who are not candidates for major surgery or who prefer to avoid long scars.34678
What is the purpose of this trial?
This trial is studying how fat grafting affects blood flow in the breast skin of patients who have had a mastectomy and radiation therapy. The goal is to see if adding fat can improve skin health. Fat grafting has been increasingly recognized as a tool to rejuvenate irradiated skin and improve skin quality in patients who have undergone radiation therapy.
Research Team
Christin A. Harless, M.D.
Principal Investigator
Mayo Clinic
Eligibility Criteria
This trial is for breast cancer patients who have had a mastectomy and are undergoing immediate reconstruction with tissue expanders or implants that require radiation therapy. It's not open to those who do not wish to participate.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Radiation
Participants undergo radiation therapy as part of their post-mastectomy treatment
Fat Grafting
Participants receive autologous fat transfer to the breast(s) to improve skin perfusion
Follow-up
Participants are monitored for radiation fibrosis and skin perfusion changes
Treatment Details
Interventions
- Fat Grafting
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor