250 Participants NeededMy employer runs this trial

CORUS-LX System for Degenerative Disc Disease

(ILIF Trial)

Recruiting at 7 trial locations
EM
Overseen ByErik M Summerside, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Providence Medical Technology, Inc.
Stay on Your Current MedsYou can continue your current medications while participating
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this clinical trial is to assess the safety and effectiveness of the study device, CORUS-LX, as an adjunct to lumbar interbody fusion, when used in combination with pedicle screw and rod constructs for the treatment of lumbosacral degenerative disease in patients requiring 2 level (L4-S1) lumbar fusion, for the treatment of symptomatic degenerative lumbosacral disc disease. The main questions it aims to answer are:

Is there fusion success at the treated posterior anatomy of each level? Is there an absence of major adverse device related events? Is there an absence of injections (steroid, facet joint, nerve block) or subsequent revision surgery at index levels for symptoms related to back or leg pain?

Researchers will compare a control arm to the treatment arm to see if research results vary from standard minimally invasive supplemental posterior fusion.

Eligible participants will undergo one of the below interventions:

* Two-level lumbar interbody fusion at L4-L5 \& L5-S1 segments, with supplemental posterior fusion performed using the study device, including pedicle screw and rod fixation.

* Two-level lumbar interbody fusion at L4-L5 \& L5-S1 segments, with standard minimally invasive supplemental posterior fusion including pedicle screw and rod fixation.

Participants will also be asked to read, understand, and sign the informed consent, attend a Screening/Baseline visit, undergo surgery for their designated intervention, and participate in 5 additional study visits where they will complete surveys for patient reported outcomes and SOC procedures. These visits will occur at the below intervals (based upon surgery day as day 0):

* 6 weeks

* 3 months

* 6 months

* 12 months

* 24 months

Who Is on the Research Team?

EM

Erik M Summerside, PhD

Principal Investigator

Providence Medical Technology

Are You a Good Fit for This Trial?

Inclusion Criteria

I am between 18 and 80 years old.
I have been diagnosed with radiculopathy in my lower back and have symptoms like pain or numbness.
My back pain severely limits my daily activities.
See 5 more

What Are the Treatments Tested in This Trial?

Interventions

  • Supplemental Posterior Fusion with Standard Technique
  • Supplemental Posterior Fusion with Study Device

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Supplemental Posterior Fusion with Study DeviceExperimental Treatment1 Intervention
Group II: Standard Supplemental Posterior Fusion TechniqueActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Providence Medical Technology, Inc.

Lead Sponsor

Trials
3
Recruited
240+