1000 Participants Needed

Tissue Collection for Vasculitis

Recruiting at 3 trial locations
SX
KD
Overseen ByKatie Doyle
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: University of Pennsylvania
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to gather tissue samples from participants in other Vasculitis Clinical Research Consortium (VCRC) studies. The collected tissues will help researchers gain a deeper understanding of vasculitis, a group of diseases that cause inflammation in blood vessels, potentially leading to new diagnostic tests and treatments. Participants already involved in a VCRC study who agree to share tissue samples may be suitable for this trial. As an unphased study, this trial offers a unique opportunity to contribute to groundbreaking research that could enhance future diagnostic and treatment options for vasculitis.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems to focus on collecting tissue samples from participants in other studies.

Why are researchers excited about this trial?

Researchers are excited about the VCRC Tissue Repository because it aims to collect and study tissue samples to better understand various vasculitis conditions. Unlike conventional treatments that focus on managing symptoms or using medications to control inflammation, this repository offers a unique opportunity to explore the underlying mechanisms of these diseases at a cellular level. By analyzing these tissue samples, scientists hope to uncover new insights that could lead to more targeted therapies and possibly even preventive strategies in the future.

Who Is on the Research Team?

PA

Peter A Merkel, MD, MPH

Principal Investigator

University of Pennsylvania

Are You a Good Fit for This Trial?

Inclusion Criteria

A participant will be deemed eligible for this study if the participant is/was enrolled in another one of the VCRC observational/longitudinal protocols (5502, 5503, 5504, 5505, 5506, 5507, 5563) and/or one of the VCRC interventional studies (5522, 5523, 5526, 5527, or 5562).

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Collection

Collection of existing tissue specimens from subjects enrolled in VCRC studies

Ongoing

Analysis

Analysis of tissue specimens and linked clinical data to identify genes that increase the risk of developing vasculitis

1 year

Follow-up

Participants are monitored for safety and effectiveness after analysis

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Tissue Collection

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Pennsylvania

Lead Sponsor

Trials
2,118
Recruited
45,270,000+

National Center for Advancing Translational Sciences (NCATS)

Collaborator

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394
Recruited
404,000+

Office of Rare Diseases (ORD)

Collaborator

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44
Recruited
12,400+

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Collaborator

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508
Recruited
1,090,000+