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CPAP for Supine Hypertension

N/A

Recruiting

Led By Italo Biaggioni, MD

Research Sponsored by Vanderbilt University Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 hours

Awards & highlights

Study Summary

This trial will assess whether CPAP can help to lower blood pressure in patients with autonomic failure who also have supine hypertension.

Who is the study for?

This trial is for patients with autonomic failure who also have high blood pressure when lying down. It's open to all races but not for medical students, pregnant women, or those at high risk like heart failure, serious coronary issues, liver problems, or a history of stroke or heart attack. People with severe allergies or asthma can't join.Check my eligibility

What is being tested?

The study is testing if using continuous positive airway pressure (CPAP) can lower blood pressure in people who experience higher blood pressure while lying down due to autonomic failure. A CPAP machine helps breathing and might affect blood pressure.See study design

What are the potential side effects?

While the trial doesn't specify side effects, common ones from CPAP include discomfort in the chest muscles, dry nose or throat, skin irritation from the mask, and sometimes feeling claustrophobic.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Supine Systolic Blood Pressure

Secondary outcome measures

Urinary volume

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: CPAP (continuous positive airway pressure)Active Control1 Intervention

Continuous positive airway pressure during the night

Group II: Placebo pill or patch or sham CPAPPlacebo Group1 Intervention

Placebo pill or patch or sham CPAP

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Vanderbilt University Medical CenterLead Sponsor

857 Previous Clinical Trials

672,181 Total Patients Enrolled

2 Trials studying Supine Hypertension

103 Patients Enrolled for Supine Hypertension

Italo Biaggioni, MDPrincipal Investigator - Vanderbilt University Medical Center

Vanderbilt University Medical Center

28 Previous Clinical Trials

1,442 Total Patients Enrolled

2 Trials studying Supine Hypertension

103 Patients Enrolled for Supine Hypertension

Media Library

continuous positive airway pressure (CPAP) (Other) Clinical Trial Eligibility Overview. Trial Name: NCT03312556 — N/A

Supine Hypertension Research Study Groups: CPAP (continuous positive airway pressure), Placebo pill or patch or sham CPAP

Supine Hypertension Clinical Trial 2023: continuous positive airway pressure (CPAP) Highlights & Side Effects. Trial Name: NCT03312556 — N/A

continuous positive airway pressure (CPAP) (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03312556 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is eligibility being granted to individuals over the age of twenty for this research endeavor?

"The study is looking for participants between the ages of 18 and 85. There are 54 trials recruiting patients who are younger than 18 years old, plus an additional 670 studies that target individuals over 65 years in age."

Answered by AI

How many participants are currently recruited for this research?

"Affirmative. According to the latest update posted on October 24th 2022, this study is actively enrolling participants and requires 12 volunteers at 1 medical facility. The trial was first launched in September 21st 2017."

Answered by AI

Are any participants being enrolled in this clinical trial at the present time?

"Per the clinicaltrials.gov website, this medical trial is still acquiring participants; it was first posted on September 21st 2017 and recently updated on October 24th 2022."

Answered by AI

Who qualifies for inclusion in this research protocol?

"To qualify for this medical trial, potential participants must have autonomic failure and be between 18-85 years old. The study is recruiting around 12 people in total."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Italo Biaggioni 2017. "Treatment of Supine Hypertension in Autonomic Failure (CPAP)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03312556.

All > Multiple System Atrophy > High Blood Pressure