Diet Modification for Chronic Kidney Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
This study aims to investigate the feasibility of increasing dietary consumption of a rich variety of fruits and vegetables (including those that are potassim-rich) in patients with chronic kidney disease through use of nutritional counselling and hyperkalemia management with patiromer
Will I have to stop taking my current medications?
The trial requires that if you are taking RASS inhibitors, beta-blockers, or diuretics, you must be on stable doses for 2 weeks. If you are taking other potassium controlling agents, you cannot participate in the trial.
Is increasing fruit and vegetable intake safe for people with chronic kidney disease?
Increasing fruit and vegetable intake is generally safe for most people, but those with advanced chronic kidney disease should be cautious due to the risk of hyperkalemia (high potassium levels in the blood). However, studies suggest that a balanced intake can be beneficial and may reduce the risk of disease progression and other health issues.12345
How does increasing fruits and vegetables differ from other treatments for chronic kidney disease?
Increasing fruits and vegetables in the diet for chronic kidney disease is unique because it helps neutralize metabolic acidosis (a condition where the body produces too much acid) and reduces harmful toxins, unlike traditional diets that limit these foods due to high potassium content. This approach also lowers phosphorus absorption, reducing cardiovascular risks, and provides essential nutrients like magnesium and vitamin K, which are often deficient in these patients.15678
What data supports the effectiveness of the treatment Fruits and Vegetable increase for Chronic Kidney Disease?
Who Is on the Research Team?
Nand Wadwha, MD
Principal Investigator
NY Health
Are You a Good Fit for This Trial?
This trial is for adults over 18 with chronic kidney disease (eGFR 15-44ml/min/1.73m2) and high potassium levels in their blood (≥5.0 mmol/L). They should be on stable doses of certain heart or blood pressure medicines for at least two weeks. People allergic to patiromer or already taking potassium controlling drugs can't join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Control Period
Participants document their normal daily consumption of fruits and vegetables in a food diary while taking Patiromer (Veltassa) daily
Dietary Intervention
Participants receive dietary/nutritional counseling and increase their fruit and vegetable intake, documenting choices in food diaries
Follow-up
Participants are monitored for safety and effectiveness after treatment, with continued use of Veltassa at the discretion of the investigator
What Are the Treatments Tested in This Trial?
Interventions
- Fruits and Vegetable increase
Find a Clinic Near You
Who Is Running the Clinical Trial?
Nand Wadhwa
Lead Sponsor