VR Technology for Pupil Disorders
(RAPD Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores a new method to detect a pupil condition called Relative Afferent Pupillary Defect (RAPD). Researchers aim to determine if a virtual reality headset combined with machine learning can identify RAPD more reliably than the traditional "swinging flashlight test," a standard eye examination method. The trial is open to individuals with eye disorders such as glaucoma or diabetic retinopathy who have been referred by their eye doctor. Participants will undergo the standard test and then use the new VR method for comparison. The goal is to determine if the VR method can detect RAPD earlier and more accurately. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance early detection methods for eye conditions.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It seems focused on testing a device for eye conditions, so it's unlikely to require changes to your medication, but you should confirm with the study team.
What prior data suggests that this VR technology is safe for detecting pupil disorders?
A previous study showed that using a virtual reality headset did not change vision, though some people found it slightly harder to focus on nearby objects. This suggests that while the headset is generally safe, prolonged use might cause slight focusing difficulties for a few individuals.
Other research has shown that the safety of these headsets depends on usage. Factors such as screen type and duration of use can affect safety. Generally, these devices are well-tolerated, but following usage guidelines is important.
Overall, virtual reality headsets are considered safe for detecting eye conditions like Relative Afferent Pupillary Defect (RAPD). Participants should feel comfortable using them in this study but should report any discomfort to the study team.12345Why are researchers excited about this trial?
Researchers are excited about using Virtual Reality Head-Mounted Displays (VR HMDs) for diagnosing pupil disorders because this technology offers a new way to assess pupil responses. Unlike traditional methods that rely on manual measurements during a swinging light test, the VR HMD provides a more standardized and potentially automated approach. This could lead to more accurate and consistent assessments of Relative Afferent Pupillary Defect (RAPD). Additionally, integrating machine learning with VR technology might improve diagnostic precision, making it easier to detect subtle changes in pupil response that are often missed with conventional techniques.
What evidence suggests that this VR technology is effective for detecting RAPD?
Research has shown that virtual reality headsets can effectively detect certain eye issues called relative afferent pupillary defects (RAPD). One study found that using these headsets for eye tests was practical and promising in spotting RAPD. In this trial, participants will undergo the standard swinging light test followed by the light test using the Virtual Reality Head-Mounted Display (VR HMD) with machine learning. This technology employs machine learning, a type of artificial intelligence that learns from data, to measure pupil reactions more accurately than traditional methods. It could help identify RAPD earlier than the usual flashlight test, leading to faster diagnosis. While more research is needed, these early results suggest that virtual reality headsets could reliably identify RAPD.25678
Who Is on the Research Team?
Kevin H Merkley, MD, MBA
Principal Investigator
University of Texas
Are You a Good Fit for This Trial?
This trial is for UTMB clinic patients aged 18-85 with known Relative Afferent Pupillary Defect (RAPD) or vision disorders like glaucoma. It's not for those outside this age range, non-English speakers, people uncomfortable with VR devices or glasses, and those with congenital pupil issues.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo the standard of care swinging flashlight test and manual pupil measurements
Intervention
Participants undergo testing with the VR HMD and ML algorithms to measure pupillary response
Follow-up
Participants are monitored for any immediate adverse effects post-intervention
What Are the Treatments Tested in This Trial?
Interventions
- Swinging Light test
- Virtual Reality Head-Mounted Display (VR HMD)
Find a Clinic Near You
Who Is Running the Clinical Trial?
The University of Texas Medical Branch, Galveston
Lead Sponsor
University of Nevada, Reno
Collaborator