VR Technology for Pupil Disorders
(RAPD Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It seems focused on testing a device for eye conditions, so it's unlikely to require changes to your medication, but you should confirm with the study team.
What data supports the effectiveness of the treatment Swinging Light test, Virtual Reality Head-Mounted Display (VR HMD) for pupil disorders?
Research shows that VR technology can be effectively used in eye care, such as detecting eye misalignment and enhancing visual skills like stereopsis (depth perception) and visual acuity (sharpness of vision). VR headsets have also been used successfully to engage children in eye tests, suggesting they could be a useful tool for pupil disorder treatments.12345
Is VR technology safe for use in treating pupil disorders?
How is the VR Head-Mounted Display treatment for pupil disorders different from other treatments?
The VR Head-Mounted Display treatment for pupil disorders is unique because it uses virtual reality technology to detect and assess eye conditions like relative afferent pupillary defects (RAPDs) through eye tracking, offering a non-invasive and interactive way to monitor and diagnose eye issues compared to traditional methods.12368
What is the purpose of this trial?
The goal of this prospective reliability study is to test the effectiveness of a commercially available, off-the-shelf virtual reality head-mounted display (VR HMD) and machine learning (ML) algorithms in detecting Relative Afferent Pupillary Defect (RAPD) in a group of subjects with known RAPD and another group with no known RAPD.The main questions it aims to answer are:* Does the use of the VR HMD and ML to replace the standard of care swinging flashlight test provide a more reliable and objective pupil measurement to detect RAPD?* Can RAPD be detected by the VR HMD and ML algorithms at an earlier stage than the standard of care swinging light test?Participants will be asked to undergo the standard of care swinging flashlight test, have their pupils manually measured, then have the test repeated using the VR HMD and ML.Researchers will compare the measurements taken manually, following the standard of care swinging light test and those recorded by the VR HMD and ML to help answer the above questions.
Research Team
Kevin H Merkley, MD, MBA
Principal Investigator
University of Texas
Eligibility Criteria
This trial is for UTMB clinic patients aged 18-85 with known Relative Afferent Pupillary Defect (RAPD) or vision disorders like glaucoma. It's not for those outside this age range, non-English speakers, people uncomfortable with VR devices or glasses, and those with congenital pupil issues.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo the standard of care swinging flashlight test and manual pupil measurements
Intervention
Participants undergo testing with the VR HMD and ML algorithms to measure pupillary response
Follow-up
Participants are monitored for any immediate adverse effects post-intervention
Treatment Details
Interventions
- Swinging Light test
- Virtual Reality Head-Mounted Display (VR HMD)
Find a Clinic Near You
Who Is Running the Clinical Trial?
The University of Texas Medical Branch, Galveston
Lead Sponsor
University of Nevada, Reno
Collaborator