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Antidepressant

Psychotherapy for Persistent Depressive Disorder (CANBIND6 Trial)

Phase 4

Recruiting

Led By Rudolf Uher, MD, PhD

Research Sponsored by Nova Scotia Health Authority

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2-52 weeks

Awards & highlights

CANBIND6 Trial Summary

This trialwill test if certain clinical factors & biomarkers predict better response to antidepressant medication or cognitive-behavioural therapy for depression, allowing for personalized treatment & improved outcomes.

Eligible Conditions

Persistent Depressive Disorder
Depression

CANBIND6 Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2-52 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2-52 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2-52 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Total score on the Montgomery Asberg Depression Rating Scale (MADRS)

Secondary outcome measures

Global-Clinical Impression scale (GCI)

Quick Inventory of Depressive Symptoms (QIDS-SR)

CANBIND6 Trial Design

2Treatment groups

Experimental Treatment

Group I: PsychotherapyExperimental Treatment1 Intervention

Cognitive Behavioral Therapy

Group II: PharmacotherapyExperimental Treatment1 Intervention

Antidepressant medication

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Cognitive Behavioral Therapy

2016

Completed Phase 4

~3120

Pharmacotherapy

2003

Completed Phase 4

~1590

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University Health Network, TorontoOTHER

1,468 Previous Clinical Trials

484,159 Total Patients Enrolled

Centre for Addiction and Mental HealthOTHER

354 Previous Clinical Trials

80,760 Total Patients Enrolled

Queen's UniversityOTHER

365 Previous Clinical Trials

120,057 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are actively participating in this experiment?

"Affirmative. Clinicaltrials.gov documents suggest that this experiment is presently enrolling participants and has been since October 31st 2016, with the latest update occurring on February 6th 2023. The trial requires a total of 360 enrollees from 1 medical facility to be completed successfully."

Answered by AI

Has the FDA issued a stamp of approval for psychotherapeutic treatments?

"With a score of 3, psychotherapy has been deemed safe based on the results from its Phase 4 trial. This signifies that this treatment is officially approved for usage."

Answered by AI

Are there any opportunities to join this investigation currently available?

"Affirmative. As evidenced on clinicaltrials.gov, the trial which was first listed in October of 2016 is still actively recruiting patients today. 360 individuals are sought from one medical site for this investigation and it has been updated as recently as February 6th 2023."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Personalized Indications for CBT and Antidepressants in Treating Depression

Rudolf Uher 2016. "Personalized Indications for CBT and Antidepressants in Treating Depression". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02752542.