Prostate-Targeted PET Imaging for Prostate Cancer

(P-PET Trial)

Overseen By Stephen Pautler, BSc MD FRCSC

Age: Any Age

Sex: Male

Trial Phase: Academic

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Disqualifiers: Unable to comply with scan time

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this study is to evaluate the imaging capabilities of a new prostate-targeted PET system (P-PET) and determine whether it could be useful in detecting prostate cancer by comparing SOC whole body PET imaging. This pilot study will include adult men who have been diagnosed with or are suspected to have prostate cancer. Participants will undergo a standard-of-care PET/CT scan followed by an additional P-PET scan designed to provide detailed images of the prostate. The images from the two scans to assess how well the P-PET system can detect prostate cancer.

Who Is on the Research Team?

Stephen Pautler, BSc MD FRCSC

Principal Investigator

St. Joseph Health Care London

Are You a Good Fit for This Trial?

Inclusion Criteria

Qualitative comparison of PET scans acquired by the P-PET vs. WB PET

Exclusion Criteria

Unable to comply with the length of scan time due to the study imaging.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Imaging

Participants undergo a standard-of-care PET/CT scan followed by a research P-PET scan to evaluate imaging capabilities

1 day

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after imaging

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Prostate-Targeted PET-Scan (P-PET)

How Is the Trial Designed?

Group I: Standard-of-care PET Scan with Additional Dynamic and P-PET imaging. Experimental Treatment 1 Intervention

This is a prospective, single-arm, pilot diagnostic study to evaluate the diagnostic study to evaluate the diagnostic accuracy of using dynamic PET, and P-PET in 25 patients with biopsy proven prostate cancer. This study will take place during the scheduled routine clinical PSMA PET/CT scan.

Who Is Running the Clinical Trial?

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials

678

Recruited

421,000+

Lawson Research Institute of St. Joseph's

Collaborator