Connect2Care for Prostate Cancer

Overseen By Adam Alexander, PhD

Age: 18+

Sex: Male

Trial Phase: Academic

Sponsor: University of Oklahoma

Disqualifiers: Outside age range, Not in Oklahoma, Others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 4 weeks

466 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests the effectiveness of two different phone apps in helping African American men learn about prostate cancer and encouraging them to get screened. The Prostate Cancer Genius App is specifically designed for African American men, offering educational content, real-time messages, and optional counseling. The US Prevention Taskforce App provides general recommendations for prostate cancer screening. The trial seeks African American men in Oklahoma, aged 45-69, who have not had a PSA test in the last two years. As an unphased trial, this study offers a unique opportunity to contribute to important research that could enhance prostate cancer awareness and screening in the community.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on using an app to improve knowledge about prostate cancer and screening.

What prior data suggests that the Connect2Care App is safe for improving prostate cancer knowledge and screening readiness?

A previous study checked the safety of the Prostate Cancer Genius App. Researchers monitored short-term side effects, and the app showed promise in improving knowledge about prostate cancer without major safety concerns. This app provides personalized educational content and real-time messages about prostate cancer risks and the benefits of PSA testing. It also includes trivia, personal stories, and optional support from prostate cancer survivors.

Designed for ease of use, especially for African American men, the app aims to increase awareness and readiness for PSA tests (a blood test for prostate cancer). Past evaluations have not reported serious side effects, suggesting the app is well-tolerated.

The Prevention Taskforce App offers evidence-based advice for prostate cancer. Although specific safety data is unavailable, a reputable health agency developed it, indicating it is likely safe and aims to inform users effectively. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Prostate Cancer Genius app because it offers a unique approach tailored specifically for African American men, who are often underserved by existing prostate cancer education and screening resources. Unlike other treatments that rely on standard medical visits and procedures, this app provides educational content and real-time messages adapted for those with lower literacy levels, making information more accessible. It also includes engaging elements like trivia and personalized counseling options from African American survivors, which can promote better understanding and empowerment. Additionally, the app allows for automated ordering of home-based PSA tests, offering a convenient and private screening option that could increase participation in early detection efforts.

What evidence suggests that this trial's apps could be effective for improving prostate cancer screening readiness among African American men?

Research has shown that the Prostate Cancer Genius App, a treatment option in this trial, can help African American men learn about prostate cancer and encourage PSA (prostate-specific antigen) screenings. Designed specifically for its users, the app simplifies understanding of prostate cancer and the importance of early screening. It also sends real-time messages and educational content to motivate users to undergo PSA tests. Early results suggest that apps like this could effectively increase awareness and promote proactive health actions among African American men at risk for prostate cancer. Thus, the Prostate Cancer Genius App may play a key role in boosting PSA testing rates through better education and personalized support. Meanwhile, the Prevention Taskforce app, another treatment option in this trial, provides on-demand access to evidence-based recommendations for prostate cancer for men aged 55 to 69. ^{1 2 3 4 6}

Who Is on the Research Team?

Jordan Neil, PhD

Principal Investigator

University of Oklahoma

Are You a Good Fit for This Trial?

This trial is for African American men aged 45-69 in Oklahoma who are not current with PSA screening as per guidelines. It aims to improve their knowledge and readiness for prostate cancer screening.

Inclusion Criteria

Self-identify as Black/African American

Live in Oklahoma

I identify as male.

Exclusion Criteria

Has taken a PSA test or has completed PSA screening within the past two years

I am willing to use a phone app for 30 days.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants use the Connect2Care App or the Prevention Taskforce App for prostate cancer education and PSA screening readiness

4 weeks

App-based intervention

Follow-up

Participants are monitored for changes in knowledge, attitudes, and PSA screening rates

4 weeks

Community Outreach

Community Health Events and Social Media Campaign to improve awareness and access to PSA screening

Ongoing throughout the trial

What Are the Treatments Tested in This Trial?

Interventions

• Prostate Cancer Genius App
• US Prevention Taskforce App

Trial Overview The Connect2Care App, designed to increase understanding and readiness for PSA testing, is being tested against the US Prevention Taskforce App over a 30-day period in a randomized control trial.

How Is the Trial Designed?

Group I: Genius app Experimental Treatment 1 Intervention

The Prostate Cancer Genius app includes the following components: (1) educational content that is consistent with existing evidence and recommendations for prostate cancer and prostate cancer screening but has been adapted for the African American male population and for adults who read at or below the 8th-grade level; (2) real-time messages about the risks of prostate cancer and the benefits of completing a PSA test, placing a special emphasis on screening considerations for individuals with a family history of prostate cancer and/or lower urinary tract symptoms (measured via the American Urological Association Symptom Score); (3) general trivia that also incorporates quiz questions about prostate cancer and the PSA test; (4) African American-specific testimonials and educational videos; (5) optional counseling by African American prostate cancer survivors; and (6) on-demand, automated ordering of a home-based PSA test.

Group II: Prevention Taskforce app Active Control 1 Intervention

The Prevention Taskforce app provides on-demand access to evidence-based recommendations for prostate cancer for men between 55 and 69 (i.e., it can be accessed as needed).

Who Is Running the Clinical Trial?

University of Oklahoma

Lead Sponsor

Trials

484

Recruited

95,900+

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT05331638

Prostate Cancer Genius App Education and Home-based ... Evaluate the preliminary efficacy of a prostate cancer prevention app on prostate cancer knowledge (primary outcome). Hypothesis: Participants (n = 40) randomly ...

2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11627590/

A pilot randomized clinical trial of a smartphone-based ... The current pilot study will test the first-of-its-kind mobile health (mHealth) app to improve prostate cancer knowledge and increase PSA screening uptake among ...

3. researchgate.net researchgate.net/profile/Adam-Alexander-4/publication/385697688_A_pilot_randomized_clinical_trial_of_a_smartphone-based_application_to_support_at-home_PSA_screening_and_culturally_tailored_prostate_cancer_education_for_African_American_men_A_study_protocol/links/67377c664a70511f0720118e/A-pilot-randomized-clinical-trial-of-a-smartphone-based-application-to-support-at-home-PSA-screening-and-culturally-tailored-prostate-cancer-education-for-African-American-men-A-study-protocol.pdf?origin=scientificContributions

A-pilot-randomized-clinical-trial-of-a-smartphone-based- ... Discussion: mHealth apps offer promise to improve prostate cancer knowledge and screening rates among AA men. Demonstrating the preliminary ...

4. centerwatch.com centerwatch.com/clinical-trials/listings/NCT07055165/connect2care-prostate-cancer-education-and-screenings-for-african-american-men

Connect2Care: Prostate Cancer Education and Screenings ... Participants in the Genius App will also have access to several culturally tailored, novel features to support at-home PSA screening. Outcomes.

5. cancer.gov cancer.gov/research/participate/clinical-trials-search/v?id=NCI-2023-04367

Evaluation of a Smartphone-Based Application for Prostate ... This clinical trial evaluates how well a new smartphone-based application (app), called Prostate Cancer Genius App (PCGA), works in providing prostate ...

6. healthpromotionresearch.org healthpromotionresearch.org/Studies/a-pilot-randomized-clinical-trial-of-a-smartphone-based-application-for-prostate-cancer-education-and-home-based-psa-screening-for-african-american-men

Active Studies | TSET Health Promotion Research ... This project proposes to develop and test the first-of-its-kind Prostate Cancer Genius App to improve knowledge of prostate cancer risk and symptoms and deliver ...