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RG-RV for Cat Allergy (VMR Trial)
VMR Trial Summary
This trial studies the effects of an inoculation on airway gene expression and remodeling in people with/without allergies to cat dander. Screening, blood draws, and pulmonary testing will be done to determine eligibility.
VMR Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowVMR Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.VMR Trial Design
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- You must be between 18 and 60 years old, able to understand and give permission to take part in the study, and have been diagnosed with allergic rhinitis by a doctor. You can't have a history of asthma, COPD, diabetes, or heart disease. You must have had symptoms of nasal congestion or sneezing or eye irritation caused by allergies in the past year. You also need to have a specific allergy to cats and regular exposure to cat dander.Criterion: You are between 18 and 60 years old, and you have mild to moderate asthma. You have not smoked much in the past, and you do not have a history of diabetes or heart disease. You also have a specific type of asthma that can be treated with the study medication.This criterion excludes people who:
- Don't follow the study rules
- Take certain respiratory medications
- Have specific test results related to their lung function
- Had a recent asthma flare-up
- Take high doses of certain medications
- Are pregnant, planning to get pregnant, or have close contacts who are pregnant
- Have certain medical conditions or age groups
- Work in healthcare or with children
- Had certain treatments or health conditions in the past year
- Have a high body mass index (BMI)
- Had certain symptoms or medical history
- Haven't taken steroid pills for 3 months
- Have a certain score on an asthma test
- Take certain blood-thinning medications
- Tested positive for COVID-19 recentlyPeople who are healthy and not part of the patient group being studied.I am either male or female.I am between 18 and 60 years old.I have never smoked, or if I did, it was less than 10 pack years and I quit over 5 years ago.I have no history of asthma, COPD, or significant respiratory issues.
- Group 1: Healthy
- Group 2: Allergic Rhinitis
- Group 3: Allergic Ashthma
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does this trial accommodate seniors aged 75 and above?
"This trial only accepts participants aged 18 to 60; however, there are 212 studies for minors and 611 trials specifically targeting seniors."
Does Allergic Rhinitis present any appreciable health risks to those affected?
"This medication is fairly safe, as indicated by its rating of 2. Although there have been trials that demonstrate some safety data, efficacy has not yet been proven in any studies."
Are there vacancies open to participants in this research effort?
"Affirmative. According to the clinicaltrials.gov website, this trial is actively enrolling patients and was initially posted on April 27th 2023 with a recent amendment made on May 5th 2023. The study requires 75 participants from 1 centre."
How many participants have enrolled in this research experiment?
"Affirmative. Clinicaltrials.gov suggests that this clinical trial, first posted on April 27th 2023, is actively recruiting individuals for the study. Just 75 patients are needed from 1 medical facility."
To whom does this research study appeal most?
"This medical trial is actively recruiting 75 individuals aged 18-60 with asthma. To qualify, participants need to be able to read and accept the terms of informed consent; they must not have a history of other respiratory diseases like COPD or rhinitis; if applicable, ex-smokers must have smoked less than 10 pack years within last 5 years prior to joining the study; they cannot suffer from diabetes or cardiovascular disease either. Furthermore, those in allergic rhinitis group are required to hold negative immunology tests for regionally relevant allergens taken at screening, or provide documentation of past 12 months' skin test results proving their aller"
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
How responsive is this trial?
Average response time
- < 2 Days
Typically responds via
Most responsive sites:
- University of Texas Medical Branch: < 48 hours
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