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PSMA-PET CT Imaging for Prostate Cancer (ESCAPE Trial)

N/A

Recruiting

Led By Himanshu Nagar, M.D.

Research Sponsored by Weill Medical College of Cornell University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 24 months

Awards & highlights

ESCAPE Trial Summary

This trial will study if a non-invasive imaging test can detect prostate cancer that would need treatment in men on active surveillance.

Who is the study for?

Men over 18 with low or favorable intermediate-risk prostate cancer, as defined by NCCN guidelines, can join. They must have a PSA level under 20 ng/ml and be able to undergo yearly PSMA-PET CT scans, prostate biopsies, and mpMRI. Those not interested in active surveillance or with prior treatments for prostate cancer cannot participate.Check my eligibility

What is being tested?

The trial is testing the effectiveness of PSMA-PET CT scans in monitoring patients with low to intermediate-risk prostate cancer who are on active surveillance. The goal is to see if this imaging technique can reliably detect the absence of significant cancer progression.See study design

What are the potential side effects?

While the document does not specify side effects related to PSMA-PET CT scans directly, generally such procedures may include discomfort at injection site, allergic reaction to contrast agents used during imaging, and exposure to radiation.

ESCAPE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 24 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~24 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Negative predictive value (NPV)

Secondary outcome measures

Number of negative scans on PSMA-PET

Number of negative scans on both PSMA-PET and mpMRI

Number of negative scans on mpMRI

+8 more

ESCAPE Trial Design

1Treatment groups

Experimental Treatment

Group I: PSMA-PET CTExperimental Treatment1 Intervention

Patients will undergo PSMA-PET CT (Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography) at baseline, 12 month and 24 month time point.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Weill Medical College of Cornell UniversityLead Sponsor

1,055 Previous Clinical Trials

1,316,095 Total Patients Enrolled

48 Trials studying Prostate Cancer

35,439 Patients Enrolled for Prostate Cancer

Himanshu Nagar, M.D.Principal InvestigatorWeill Medical College of Cornell University

6 Previous Clinical Trials

317 Total Patients Enrolled

3 Trials studying Prostate Cancer

305 Patients Enrolled for Prostate Cancer

Timothy Mcclure, M.D.Principal InvestigatorWeill Medical College of Cornell University

Media Library

PSMA-PET CT Clinical Trial Eligibility Overview. Trial Name: NCT05948657 — N/A

Prostate Cancer Research Study Groups: PSMA-PET CT

Prostate Cancer Clinical Trial 2023: PSMA-PET CT Highlights & Side Effects. Trial Name: NCT05948657 — N/A

PSMA-PET CT 2023 Treatment Timeline for Medical Study. Trial Name: NCT05948657 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research accept adults over eighteen years of age?

"The parameters for this clinical trial indicate that it is open to individuals between 18 and 90 years old. There are 67 trials specifically targeting patients below the age of majority, whereas there are 1,330 studies tailored towards people who have surpassed 65 years of life."

Answered by AI

Is the research team still enrolling participants for this investigation?

"As the information on clinicaltrials.gov suggests, this specific trial is not actively recruiting patients anymore; it was initially posted on July 1st 2023 and last reviewed on the 6th of that same month. Nonetheless, 1333 other trials are presently accepting participants across multiple sites."

Answered by AI

Does my condition conform to the requirements of this trial?

"Qualifications for this medical experiment mandate that the participants have to be between 18 and 90 years old, as well as suffering from prostate cancer. A maximum of 200 eligible volunteers can participate in this research endeavour."

Answered by AI

What is the current total of medical centers conducting this research?

"Currently, this medical trial is accepting participants in 4 distinct centres. These include San Francisco, Cleveland and Dallas. To reduce travel fatigue, it may be helpful to select the nearest site for your participation."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr

2024. "Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05948657.

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