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Fructose Diets for Prediabetes
Study Summary
This trial will study how fructose affects blood sugar and fat production.
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am prediabetic or have high insulin but not diabetic.You have hepatitis or HIV infection.Your body mass index (BMI) is between 22 and 35.I have had surgery to help with weight loss.My liver is healthy and my liver enzyme levels are not more than twice the normal limit.I have lost or gained more than 5% of my body weight in the last 6 months.I have type 1 or type 2 diabetes.I have had cancer and haven't used any diabetes or cholesterol drugs in the last 6 months.Your fasting insulin, fasting glucose, and HbA1c levels are within specific normal ranges.My cholesterol or triglyceride levels are very high for my age and sex.My blood hemoglobin or hematocrit levels are low for my gender.I have conditions that affect my insulin sensitivity and fat metabolism.
- Group 1: High fructose meal, with fructose label
- Group 2: High fructose meal, with pyruvate label
- Group 3: Low fructose meal, with fructose label
- Group 4: Low fructose meal, with pyruvate label
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Do I meet the qualifications for taking part in this research endeavor?
"The requirements for being accepted into this medical trial necessitate that patients have insulin resistance and be a part of the 20-55 demographic. In total, 36 individuals will be granted entry to participate."
Do elderly individuals aged 70 or above qualify for this experiment?
"This clinical trial requires that all participants are at least 20 years of age, but no older than 55."
What objectives are researchers expecting to achieve from this trial?
"This 6-hour trial aims to assess Hepatic fractional de novo lipogenesis in triglyceride rich lipoprotein (TRL). Additionally, this experiment will measure Extrasplanchnic fructose through total plasma fructose analysis, serum glucose concentration with fasting and postprandial serum triglycerides levels, Whole body fructose oxidation using 13C atom % excess in exhaled breath, and VCO2 via indirect calorimetry."
What is the current enrollment rate for this research project?
"Affirmative, the information presented on clinicaltrials.gov specifies that this trial is actively recruiting participants. This medical initiative was initially posted 15th September 2019 and has been recently modified 25th April 2022; 36 volunteers are required from a single site."
Are new participants being recruited for this clinical research endeavor?
"Affirmative, according to the clinicaltrials.gov website this research endeavor is actively looking for suitable patients. It was first published on September 15th 2019 and its most recent update occurred April 25th 2022. 36 individuals are required at a single trial site in order for it to be completed successfully."
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