Constant High for Methamphetamine Abuse

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Advocate Health Care, Chicago, IL
Methamphetamine Abuse+4 More
DynamiCare app (app-based contingency management) - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

The OVERALL AIM is to assess whether app-based incentives are effective for older adults and to quantify the associations between age and both the efficacy and take-up of app-based incentives. This will allow us to determine if older adults with substance use disorders (SUDs) are willing to engage with app-based incentives and whether they perform similarly to their younger counterparts. Because the study will leverage data from an existing study on app-based incentives, a small add-on study is sufficient to address these three aims. This aim will be achieved while simultaneously gathering data that will shed light on the two aims of the first phase of the study: whether app-based incentives are effective overall, and how to optimize the size of incentives over time to maximize their effectiveness.

Eligible Conditions

  • Methamphetamine Abuse
  • Opioid Use Disorder (OUD)
  • Cocaine Use Disorders

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Methamphetamine Abuse

Study Objectives

2 Primary · 1 Secondary · Reporting Duration: Through study completion, an average of 1 year

3 months
Drug-negative saliva tests
Longest period of continuous abstinence
Year 1
App uptake

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Other trials for Methamphetamine Abuse

Trial Design

7 Treatment Groups

Constant High
1 of 7
De-Escalating Low
1 of 7
Escalating High
1 of 7
Constant Low
1 of 7
De-Escalating High
1 of 7
Escalating Low
1 of 7
Control
1 of 7
Experimental Treatment
Non-Treatment Group

600 Total Participants · 7 Treatment Groups

Primary Treatment: Constant High · Has Placebo Group · Phase 2

Constant High
Behavioral
Experimental Group · 1 Intervention: DynamiCare app (app-based contingency management) · Intervention Types: Behavioral
De-Escalating Low
Behavioral
Experimental Group · 1 Intervention: DynamiCare app (app-based contingency management) · Intervention Types: Behavioral
Escalating High
Behavioral
Experimental Group · 1 Intervention: DynamiCare app (app-based contingency management) · Intervention Types: Behavioral
Constant Low
Behavioral
Experimental Group · 1 Intervention: DynamiCare app (app-based contingency management) · Intervention Types: Behavioral
De-Escalating High
Behavioral
Experimental Group · 1 Intervention: DynamiCare app (app-based contingency management) · Intervention Types: Behavioral
Escalating Low
Behavioral
Experimental Group · 1 Intervention: DynamiCare app (app-based contingency management) · Intervention Types: Behavioral
Control
Behavioral
ShamComparator Group · 1 Intervention: Sham control · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: through study completion, an average of 1 year
Closest Location: Advocate Health Care · Chicago, IL
Photo of Chicago  1Photo of Chicago  2Photo of Chicago  3
2009First Recorded Clinical Trial
1 TrialsResearching Methamphetamine Abuse
5 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 8 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have a minimum age of 18 years old.
You have used non-medical opioids, cocaine, and/or methamphetamine within the last 21 days.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References