Genomic Profiling for Cancer
(ASAP Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore the genetic makeup of individuals with pre-cancerous conditions or cancer to understand the drivers of these diseases. By analyzing participants' DNA and proteins, the researchers hope to discover new markers that could aid in diagnosing and treating various cancers. Participants should have a pre-cancerous condition or a cancer diagnosis and be involved in medical evaluation or follow-up. Joining this study might not only assist with personal treatment options but also advance cancer research for future patients. As an unphased trial, this study offers participants the opportunity to contribute to groundbreaking research that could lead to significant advancements in cancer diagnosis and treatment.
Why are researchers excited about this trial?
Researchers are excited about the Avera Cancer Sequencing and Analytics Protocol (ASAP) because it represents a cutting-edge approach to understanding cancer on a genetic level. Unlike traditional treatments that target the tumor as a whole, this protocol uses advanced sequencing technology to analyze the unique genetic makeup of individual cancers. By doing so, it aims to identify specific genetic mutations that can be targeted with precision therapies. This personalized approach could lead to more effective and tailored treatments, potentially improving outcomes and reducing side effects for cancer patients.
Who Is on the Research Team?
Rachel Elsey, PharmD
Principal Investigator
Avera Cancer Institute
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Molecular Profiling
Comprehensive molecular profiling including somatic tumor testing, whole exome sequencing, whole transcriptome sequencing, proteomics, and selected instances of whole genome sequencing
Hereditary Cancer Testing
Broad hereditary cancer testing with implications in screening, prognosis, and therapeutics
Follow-up
Participants are monitored for safety and effectiveness after testing, with electronic health records abstracted, curated, annotated, and linked to genomic information
Biobanking
Participants may consent to have their samples stored in a biobank for future research
What Are the Treatments Tested in This Trial?
Find a Clinic Near You
Who Is Running the Clinical Trial?
Avera McKennan Hospital & University Health Center
Lead Sponsor
Sema4
Collaborator
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