Drug Effects for Postural Orthostatic Tachycardia Syndrome
Trial Summary
Do I need to stop my current medications for the trial?
The trial protocol does not specify whether you need to stop taking your current medications.
What safety data exists for the treatment of Postural Orthostatic Tachycardia Syndrome?
How does the drug differ from other treatments for postural orthostatic tachycardia syndrome?
What is the purpose of this trial?
The purpose of this study is to describe the mechanism of orthostatic intolerance, relying on cardiovascular physiological studies. The syndrome is of undetermined etiology, but the syndrome causes impairment of a number of young adults, females more than males, with symptoms of tachycardia, fatigue, lightheadedness, palpitations, blurred vision, chest discomfort, difficulty concentrating, and dizziness with the upright posture. It is believed that many different pathophysiological processes can give rise to this disorder.
Research Team
David Robertson, M.D.
Principal Investigator
Vanderbilt University
Eligibility Criteria
This trial is for young adults, especially females, who experience rapid heartbeat, fatigue, lightheadedness, and other symptoms when standing up (Orthostatic Intolerance). Participants must be able to give informed consent.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Cardiovascular Physiological Studies
Participants undergo cardiovascular physiological studies to describe the mechanism of orthostatic intolerance
Follow-up
Participants are monitored for safety and effectiveness after the physiological studies
Treatment Details
Interventions
- DAXOR
- Intrinsic Heart Rate
- QSweat
Find a Clinic Near You
Who Is Running the Clinical Trial?
Satish R. Raj
Lead Sponsor
National Institutes of Health (NIH)
Collaborator