Study Summary
This trial is to study the effects of different drugs on people with a syndrome that causes symptoms like a fast heart rate, fatigue, and dizziness when standing up.
Eligible Conditions
- Rapid Heartbeat
- Postural Orthostatic Tachycardia Syndrome (POTS)
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 5 Secondary · Reporting Duration: 3 hours
1 day
Physiological abnormalities in orthostatic intolerance
blood volume
1 hour
intrinsic heart rate
2 hours
quantitative sweat testing
3 hours
norepinephrine spillover
residual sympathetic function after pharmacological autonomic blockade
Trial Safety
Safety Progress
Trial Design
0 Treatment Group
100 Total Participants · 0 Treatment Group
Primary Treatment: Treatment · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 3 hours
Who is running the clinical trial?
National Institutes of Health (NIH)NIH
2,440 Previous Clinical Trials
24,567,287 Total Patients Enrolled
Satish R. RajLead Sponsor
6 Previous Clinical Trials
430 Total Patients Enrolled
David Robertson, MDPrincipal InvestigatorVanderbilt University
3 Previous Clinical Trials
138 Total Patients Enrolled
Eligibility Criteria
Age 18 - 80 · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:References
- Mustafa, Hossam I., Emily M. Garland, Italo Biaggioni, Bonnie K. Black, William D. Dupont, David Robertson, and Satish R. Raj. 2011. “Abnormalities of Angiotensin Regulation in Postural Tachycardia Syndrome”. Heart Rhythm. Elsevier BV. doi:10.1016/j.hrthm.2010.11.009.
- Satish R. Raj 1996. "Pathophysiology of Orthostatic Intolerance". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00608725.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Conditions
Cancer Related
Treatments