Oxygen Gas for Inhalation for Postoperative Respiratory Failure

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Stanford University School of Medicine, Stanford, CA
Postoperative Respiratory Failure+2 More
Oxygen Gas for Inhalation - Other
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.

Eligible Conditions

  • Postoperative Respiratory Failure
  • Ventilatory Depression

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: Ninety -minute period beginning immediately post-anesthesia.

Ninety -minute period beginning immediately post-anesthesia.
Apnea / hypopnea index (AHI)
Transcutaneous partial pressure of carbon dioxide (TcPCO2)

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

"Conservative O2 Supplementation"
1 of 2
"Liberal O2 Supplementation"
1 of 2
Active Control
Experimental Treatment

60 Total Participants · 2 Treatment Groups

Primary Treatment: Oxygen Gas for Inhalation · No Placebo Group · N/A

"Liberal O2 Supplementation"
Other
Experimental Group · 1 Intervention: Oxygen Gas for Inhalation · Intervention Types: Other
"Conservative O2 Supplementation"
Other
ActiveComparator Group · 1 Intervention: Oxygen Gas for Inhalation · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: ninety -minute period beginning immediately post-anesthesia.

Trial Background

Prof. Anthony Doufas, Professor, Department of Anesthesiology, Perioperative and Pain Medicine
Principal Investigator
Stanford University
Closest Location: Stanford University School of Medicine · Stanford, CA
2010First Recorded Clinical Trial
1 TrialsResearching Postoperative Respiratory Failure
672 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are scheduled to undergo robotic-assisted radical laparoscopic nephrectomy.
You have a ASA physical status of I, II, or III.
You have a body mass index (BMI) less than 40 kg/m2.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.