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Gas

Oxygen Gas for Inhalation for Respiratory Insufficiency

N/A
Recruiting
Led By Anthony Doufas, MD, PhD
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up ninety -minute period beginning immediately post-anesthesia.
Awards & highlights

Study Summary

This trial will study the effects of oxygen on post-anesthesia recovery.

Who is the study for?
This trial is for adults in good to moderate health (ASA I-III), with a BMI under 40, who are scheduled for robotic-assisted kidney removal surgery. It's not open to those with chronic lung disease, severe brain/heart/lung conditions, major psychiatric or untreated thyroid issues, chronic pain on opioid treatment, low blood count or significant blood loss during surgery.Check my eligibility
What is being tested?
The study tests if breathing high levels of oxygen after general anesthesia helps patients recover their normal breathing faster. Participants will be randomly assigned to receive extra oxygen or not after they wake up from anesthesia and will be monitored for 90 minutes.See study design
What are the potential side effects?
Inhaling high levels of oxygen can sometimes cause dryness or irritation in the throat and lungs. In rare cases, prolonged exposure may lead to lung damage or changes in blood oxygen levels.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~ninety -minute period beginning immediately post-anesthesia.
This trial's timeline: 3 weeks for screening, Varies for treatment, and ninety -minute period beginning immediately post-anesthesia. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Transcutaneous partial pressure of carbon dioxide (TcPCO2)
Secondary outcome measures
Apnea / hypopnea index (AHI)

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: "Liberal O2 Supplementation"Experimental Treatment1 Intervention
Oxygen administration will be titrated to an SpO2 > 96%.
Group II: "Conservative O2 Supplementation"Active Control1 Intervention
Oxygen administration will be titrated to a oxyhemoglobin saturation (SpO2) between 90 and 94%.

Find a Location

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,379 Previous Clinical Trials
17,333,333 Total Patients Enrolled
1 Trials studying Respiratory Depression
80 Patients Enrolled for Respiratory Depression
Anthony Doufas, MD, PhDPrincipal InvestigatorProfessor, Department of Anesthesiology, Stanford University Medical School
2 Previous Clinical Trials
18 Total Patients Enrolled

Media Library

Oxygen Gas for Inhalation (Gas) Clinical Trial Eligibility Overview. Trial Name: NCT05379673 — N/A
Respiratory Depression Research Study Groups: "Conservative O2 Supplementation", "Liberal O2 Supplementation"
Respiratory Depression Clinical Trial 2023: Oxygen Gas for Inhalation Highlights & Side Effects. Trial Name: NCT05379673 — N/A
Oxygen Gas for Inhalation (Gas) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05379673 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this trial currently in the process of enrolling participants?

"Right. According to clinicaltrials.gov, this medical study is currently accepting participants; it was first posted on October 4th 2022 and recently updated on October 17th 2022. The research team seeks 60 volunteers from a single location for the trial."

Answered by AI

What is the maximum sample size for this experimental trial?

"Indeed, the clinicaltrials.gov listing shows that this investigation is actively seeking volunteers. It was first published on October 4th 2022 and has been most recently revised on October 17th 2022. The research team needs to enroll 60 participants from a single site."

Answered by AI

Is admission for the trial open to individuals below retirement age?

"The eligibility requirements for this clinical trial specify that applicants must be between 18 and 70 years of age."

Answered by AI
~28 spots leftby Jul 2025