Supervised Feeding for Peanut Allergy
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether participants need to stop taking their current medications.
What data supports the effectiveness of the treatment Supervised Clinical Feeding Intervention for peanut allergy?
Research shows that oral immunotherapy (OIT) for peanut allergy, which involves gradually increasing exposure to peanut protein, has been effective in helping children and adolescents tolerate higher amounts of peanut protein without severe allergic reactions. This approach has been shown to reduce symptom severity and improve quality of life for patients and their families.12345
Is supervised feeding for peanut allergy generally safe for humans?
How does the Supervised Clinical Feeding Intervention treatment for peanut allergy differ from other treatments?
The Supervised Clinical Feeding Intervention for peanut allergy is unique because it involves a supervised approach to gradually introducing peanuts to those with allergies, aiming to desensitize them and reduce the risk of severe reactions. This method contrasts with traditional avoidance strategies and offers a proactive way to manage peanut allergies by building tolerance.5691011
What is the purpose of this trial?
Peanut allergies affect approximately 2.5% of children; are associated with significant mortality, morbidity, and economic costs; and often lead to persistent peanut allergies in adulthood. We now know however that early introduction of peanut products to infants prior to age 7 months and maintained in the diet regularly significantly reduces the rate of peanut allergies. Unfortunately, recent research shows that even when parents know the recommendations to feed peanut products early and often, \<50% of parents report introducing peanuts by age 9 months, \<45% are offering peanut products several times a week, and \<20% are offering the recommended 2 teaspoons at each feeding. Many parents cite a fear of reactions or a lack of knowledge on how to safely feed peanut products at this age. While there are recommendations to offer the first feeding in clinic this has not been widely implemented in general pediatrics clinics and we have no research to say this is an effective way to increase peanut consumption at home. This research is being conducted to assess the effectiveness of a supervised peanut feeding clinic in a pediatric office to increase rate of guideline recommended peanut consumption in infants by 9 months of age.
Eligibility Criteria
This trial is for infants who have not yet reached 7 months of age, aiming to prevent peanut allergies by introducing peanut products early. Parents must be willing to follow the feeding intervention and guidelines provided. Infants with known severe food allergies or conditions that could interfere with the study are likely excluded.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants in the intervention arm are invited to a supervised feeding clinic visit where infants are fed peanut butter in a monitored clinical setting.
Follow-up
Participants are monitored for peanut introduction and frequency of feeding at home.
Treatment Details
Interventions
- Supervised Clinical Feeding Intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
Boston Children's Hospital
Lead Sponsor