← Back to Search

Deep Brain Stimulation

Burst-Type Deep Brain Stimulation for Parkinson's Disease (BURST Trial)

N/A

Recruiting

Research Sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months

Awards & highlights

BURST Trial Summary

This trial evaluates a new type of brain stimulation to improve effectiveness & durability of brain stimulation treatments.

Who is the study for?

This trial is for Parkinson's Disease patients who've had bilateral DBS-STN implants for at least 6 months, can use a DBS controller, and have stable medication and DBS settings. It excludes those with non-Boston scientific Genus/Gevia DBS tech, cognitive decline, or inability to complete follow-ups.Check my eligibility

What is being tested?

The study compares burst-type DBS electrical stimulation programming—a new protocol delivering intermittent bursts of stimulation—with the standard continuous high-frequency stimulation in managing Parkinson's symptoms.See study design

What are the potential side effects?

Potential side effects may include discomfort at the implant site, headache, temporary worsening of Parkinson's symptoms during adjustment periods, and rare risks associated with brain surgery like infection or bleeding.

BURST Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Unified Parkinson's Disease Rating Scale (UPDRS) v-III Motor Examination Score

BURST Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Experimental/Burst-type programmingExperimental Treatment1 Intervention

Burst-type DBS electrical stimulation

Group II: Standard of care programmingActive Control1 Intervention

Standard of care DBS electrical stimulation

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)Lead Sponsor

47 Previous Clinical Trials

13,074 Total Patients Enrolled

Boston Scientific CorporationIndustry Sponsor

719 Previous Clinical Trials

933,065 Total Patients Enrolled

Media Library

Burst-type DBS electrical stimulation programming (Deep Brain Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT05753449 — N/A

Parkinson's Disease Research Study Groups: Standard of care programming, Experimental/Burst-type programming

Parkinson's Disease Clinical Trial 2023: Burst-type DBS electrical stimulation programming Highlights & Side Effects. Trial Name: NCT05753449 — N/A

Burst-type DBS electrical stimulation programming (Deep Brain Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05753449 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible for me to become a participant in this trial?

"Applicants hoping to be accepted into this clinical trial should meet the criteria of being 18-85 years old and suffering from Parkinson's disease. At present, 5 patients are admitted for evaluation."

Answered by AI

Does this trial accept participants below the age of 25?

"This clinical trial is open to those aged 18-85 years old. Separately, there are 25 trials dedicated to minors and 481 specifically tailored for senior citizens."

Answered by AI

How many participants are being observed for this experiment?

"Yes, the data on clinicaltrials.gov confirms that this medical study is actively seeking participants. The trial was initiated on August 24th 2022 and has most recently been updated on March 1st 2023. There are 5 places available at a single site for potential enrollees."

Answered by AI

Is enrollment for this study still available?

"Affirmative. Clinicaltrials.gov asserts that this clinical research is actively accepting participants, with 5 individuals being accepted at a single location since its inception on August 24th 2022 and last edit on March 1st 2023."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Burst-Type Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease

Nestor Tomycz 2022. "Burst-Type Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05753449.