Rehabilitation Approaches for Freezing of Gait in Parkinson's Disease
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it excludes those who have had a recent change in medication. It's best to discuss your specific situation with the trial coordinators.
What data supports the effectiveness of the treatment TURN-IT FOG for freezing of gait in Parkinson's disease?
Is the TURN-IT FOG treatment safe for humans?
How is the TURN-IT FOG treatment different from other treatments for freezing of gait in Parkinson's disease?
The TURN-IT FOG treatment is unique because it focuses on rehabilitation approaches specifically designed to address freezing of gait in Parkinson's disease, which may not respond well to medications. Unlike other treatments, it may incorporate action observation strategies to enhance physical training, potentially offering a novel way to improve gait control and reduce freezing episodes.245910
What is the purpose of this trial?
The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable sensors, and 2) to explore whether two different rehabilitation intervention can reduce FOG and improve daily life mobility in people with FOG sufficiently to justify a clinical trial.Participants will:* Be randomly assigned to one of two intervention groups (turning-focused agility exercise or strength-based exercise)* Have one-on-one training sessions three times per week for 6 weeks* Perform in-lab assessments before beginning and after completing the study intervention* Use wearable mobility sensors during daily life to measure their walking and balance
Research Team
Martina Mancini, PhD
Principal Investigator
Oregon Health and Science University
Eligibility Criteria
This trial is for people aged 50-80 with Parkinson's Disease who experience Freezing of Gait, can follow directions, and are able to stand and walk without help. They should be in moderate stages of the disease (stages II-IV) and able to commit to a 6-week exercise program. Those with severe cognitive issues or other health problems affecting gait, recent medication changes, or unable to do moderate exercise cannot join.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are randomly assigned to one of two intervention groups and have one-on-one training sessions three times per week for 6 weeks
Follow-up
Participants perform in-lab assessments before beginning and after completing the study intervention and use wearable mobility sensors during daily life to measure their walking and balance
Treatment Details
Interventions
- TURN-IT FOG
Find a Clinic Near You
Who Is Running the Clinical Trial?
Oregon Health and Science University
Lead Sponsor
Michael J. Fox Foundation for Parkinson's Research
Collaborator