Your session is about to expire
← Back to Search
Non-invasive Brain Stimulation
tDCS for Cognitive Impairment in Parkinson's Disease (tDCS-PD-fMRI Trial)
N/A
Recruiting
Research Sponsored by University of Manitoba
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Patients must meet diagnostic criteria for idiopathic Parkinson's disease, defined as the presence of two or more of the cardinal clinical features of PD in the absence of known causes of parkinsonism such as encephalitis or neuroleptic treatment
Age > 40
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 month
Awards & highlights
tDCS-PD-fMRI Trial Summary
This trial aims to use a novel personalized network analysis approach to elucidate the mechanisms of the effect of tDCS on cognitive dysfunction in non-demented PD patients.
Who is the study for?
This trial is for English-speaking adults over 40 with Parkinson's Disease who can consent and have at least two classic symptoms without other known causes. They should not be demented, as determined by a specific cognitive test, and must not have severe movement issues that could affect scans.Check my eligibility
What is being tested?
The study tests if high-definition transcranial direct current stimulation (tDCS) on the prefrontal cortex can improve cognitive function in non-demented Parkinson's patients by affecting brain connectivity.See study design
What are the potential side effects?
Potential side effects of tDCS may include discomfort at the electrode site, itching or tingling during stimulation, headache, fatigue, nausea or insomnia. Serious risks are rare but may include seizures.
tDCS-PD-fMRI Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have been diagnosed with Parkinson's disease based on having at least two main symptoms.
Select...
I am over 40 years old.
tDCS-PD-fMRI Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 1 month
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 month
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
cognitive performance in neuropsychological tests
tDCS-PD-fMRI Trial Design
2Treatment groups
Active Control
Placebo Group
Group I: Real tDCS rightActive Control1 Intervention
Real anodal tDCS (right DLPFC)
Group II: Sham tDCSPlacebo Group1 Intervention
sham tDCS (30sec ramp-up and 3sec ramp-down)
Find a Location
Who is running the clinical trial?
Parkinson Society CanadaOTHER
3 Previous Clinical Trials
119 Total Patients Enrolled
University of ManitobaLead Sponsor
595 Previous Clinical Trials
199,490 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- My mental health will be checked by a specialist.I experience unusual movement or sensory symptoms not typical for Parkinson's disease.I am not pregnant or breastfeeding.You have other health conditions that can change the balance of minerals in your body or make you more likely to have seizures.I have severe involuntary movements, especially of the head, that could affect scan quality.You have trouble remembering things and solving problems, as measured by a test.My family has a history of epilepsy.You have an abnormal MRI, metal implants, or a heart pacemaker.I have a history of severe neurological issues or take medication that lowers seizure threshold.I have been diagnosed with Parkinson's disease based on having at least two main symptoms.I have very high blood pressure.I have a heart condition.I am over 40 years old.
Research Study Groups:
This trial has the following groups:- Group 1: Sham tDCS
- Group 2: Real tDCS right
Awards:
This trial has 0 awards, including:Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How many participants are involved in this experimental research?
"Affirmative. Details on clinicaltrials.gov verify that this research study, which was submitted to the website on March 22nd 2017, is actively seeking participants. The trial requires 36 patients from a single medical facility to begin their investigation."
Answered by AI
Is there still an opportunity to participate in this trial?
"The study, initially posted on March 22nd 2017, is actively recruiting patients as evidenced by data hosted on clinicaltrials.gov and most recently edited April 11th 2022."
Answered by AI
Recent research and studies
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger