Brief intervention (BI) for Opioid Use Disorder

University of Michigan, Ann Arbor, MI
Opioid Use DisorderBrief intervention (BI) - Behavioral
Eligibility
16 - 30
All Sexes
What conditions do you have?
Select

Study Summary

This trial will develop and test interventions to prevent opioid misuse and addiction in young adults ages 16-30, initiated during an emergency department visit and continued post-discharge via telehealth.

Eligible Conditions
  • Opioid Use Disorder

Treatment Effectiveness

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: 3, 6, and 12 months

Month 12
Change in days of opioid misuse
Change in impaired driving
Change in opioid misuse
Change in other drug and alcohol use
Change in overdose risk behaviors
Change in substance use consequences

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

4 Treatment Groups

Enhanced Usual Care (EUC) then EUC
1 of 4
Brief intervention (BI) then Portal
1 of 4
Brief intervention (BI) then Enhanced Usual Care (EUC)
1 of 4
Enhanced Usual Care (EUC) then Portal
1 of 4

Active Control

Experimental Treatment

1280 Total Participants · 4 Treatment Groups

Primary Treatment: Brief intervention (BI) · No Placebo Group · N/A

Brief intervention (BI) then PortalExperimental Group · 2 Interventions: Brief intervention (BI), Portal · Intervention Types: Behavioral, Behavioral
Brief intervention (BI) then Enhanced Usual Care (EUC)Experimental Group · 2 Interventions: Brief intervention (BI), Enhanced Usual Care (EUC) · Intervention Types: Behavioral, Behavioral
Enhanced Usual Care (EUC) then PortalExperimental Group · 2 Interventions: Portal, Enhanced Usual Care (EUC) · Intervention Types: Behavioral, Behavioral
Enhanced Usual Care (EUC) then EUC
Behavioral
ActiveComparator Group · 1 Intervention: Enhanced Usual Care (EUC) · Intervention Types: Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Portal
2011
N/A
~100
Enhanced Usual Care (EUC)
2015
Completed Phase 1
~3550

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3, 6, and 12 months

Who is running the clinical trial?

University of MichiganLead Sponsor
1,670 Previous Clinical Trials
6,420,355 Total Patients Enrolled
National Institute on Drug Abuse (NIDA)NIH
2,301 Previous Clinical Trials
2,021,137 Total Patients Enrolled
Erin Bonar, PhDPrincipal InvestigatorUniversity of Michigan
1 Previous Clinical Trials
300 Total Patients Enrolled
Maureen Walton, PhDPrincipal InvestigatorUniversity of Michigan

Eligibility Criteria

Age 16 - 30 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are between 16 and 30 years old.
You use prescription opioids and have other risk factors such as misusing marijuana, other drugs, or alcohol, or having depression or suicidal thoughts. Or, you misuse opioids, either by taking more than prescribed or using illegal opioids like heroin or fentanyl.

Frequently Asked Questions

How many participants are currently participating in this trial?

"Correct. Based on the information present in clinicaltrials.gov, this medical trial is currently recruiting. It was first announced on April 1st 2021 and its most recent update occurred July 12th 2022; 1280 participants are sought to be enrolled at a single site." - Anonymous Online Contributor

Unverified Answer

Are there still vacancies available in this clinical research project?

"As indicated on the clinicaltrials.gov website, this trial is in search of participants and was first posted on April 1st 2021 with its most recent update being July 12th 2022." - Anonymous Online Contributor

Unverified Answer

Is participation in this medical trial open to the public?

"This trial is seeking a cohort of 1280 adolescents and young adults between 16 and 30 years old who have engaged in opioid abuse. In order to be eligible, participants must meet the requisites detailed as follows: evidence of prescription opioid use combined with at least one other risk factor (such as illicit drug or alcohol misuse, depression or suicidal ideation); proof that they are currently receiving care in Michigan Medicine's emergency department; an age range of 16-30." - Anonymous Online Contributor

Unverified Answer

Is the minimum age for participation in this clinical trial over 25 years old?

"This clinical trial is recruiting 16 to 30 year olds. There are 30 studies open for minors and 338 studies available for seniors aged 65 and over." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.