Interval Exercise for COPD and Sleep Apnea
Trial Summary
What is the purpose of this trial?
The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to study validated outcomes in 3 of these domains: 1) participation in life situations; 2) physical activity; and 3) cardiovascular health. The investigators long-term goal is to develop an exercise strategy tailored to Veterans with OS which will reduce the risk of functional decline through increased PA.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment Exercise, Physical Activity, Workout, Fitness Training for COPD and Sleep Apnea?
Research shows that increasing physical activity can improve health outcomes for people with COPD, and interval exercise training can enhance exercise capacity and reduce breathlessness. Although the improvements are not always clinically significant, these findings suggest that exercise can be beneficial for managing COPD.12345
Is interval exercise safe for people with COPD and sleep apnea?
How does interval exercise differ from other treatments for COPD and sleep apnea?
Interval exercise is unique because it involves short bursts of intense activity followed by rest, which can improve exercise capacity and reduce breathlessness more effectively than continuous exercise. This approach is particularly beneficial for COPD and sleep apnea patients, as it can enhance muscle function and reduce sleep apnea severity without the need for medication.210111213
Research Team
Madalina Macrea, MD PhD
Principal Investigator
Salem VA Medical Center, Salem, VA
Eligibility Criteria
This trial is for veterans with Overlap Syndrome, which means they have both COPD and OSA. They must show cognitive function with a MoCA score over 20. Those who already do structured exercise, need daytime oxygen, have recent heart issues or hospitalization, orthopedic problems limiting walking, or a high fall risk cannot join.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo moderate intensity interval training (MIIT) or maintain routine activity level for 12 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Exercise
Find a Clinic Near You
Who Is Running the Clinical Trial?
VA Office of Research and Development
Lead Sponsor