40 Participants NeededMy employer runs this trial

Employment Services for Obsessive-Compulsive Disorder

BS
SR
Overseen BySapana R. Patel, Ph.D.
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: New York State Psychiatric Institute
Must be taking: Psychiatric medications
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help people with obsessive-compulsive disorder (OCD) find and maintain employment. Participants will undergo exposure and response prevention therapy, a form of Cognitive Behavioral Therapy (CBT) for OCD. The trial will compare two employment support models: Individual Placement and Support (personalized job assistance) and Standard Vocational Services (general job assistance). It suits those living in New York State who are currently unemployed, have a primary diagnosis of OCD, and seek competitive employment. As an unphased trial, this study provides a unique opportunity to explore innovative employment support strategies tailored for individuals with OCD.

Will I have to stop taking my current medications?

If you are currently on psychiatric medication, you need to be on a stable dose for at least 6 weeks and stay on that dose for the first three months of the therapy.

What prior data suggests that these employment service models are safe for people with OCD?

Research has shown that Exposure and Response Prevention (ERP), a therapy used in this trial, is a safe and well-tolerated treatment for obsessive-compulsive disorder (OCD). Studies indicate that ERP significantly improves OCD symptoms without causing serious side effects. It is widely accepted as a first-choice treatment for OCD. Approximately 50-60% of patients who complete ERP experience major improvements. Therefore, it is generally considered a safe option for managing OCD.12345

Why are researchers excited about this trial?

Researchers are excited about these treatments for Obsessive-Compulsive Disorder (OCD) because they combine employment support with Cognitive Behavioral Therapy (CBT), specifically the Exposure and Response Prevention (ERP) approach. Unlike traditional treatments that focus solely on CBT for OCD, this trial integrates job placement support, which is a novel approach. The experimental arm utilizes Individual Placement and Support (IPS), which involves personalized help from an employment specialist, potentially enhancing the effectiveness of CBT by addressing employment challenges that can exacerbate OCD symptoms. This dual approach could provide a more holistic solution by simultaneously targeting mental health and employment needs.

What evidence suggests that this trial's treatments could be effective for OCD?

Research has shown that exposure and response prevention (ERP), a type of therapy, effectively treats obsessive-compulsive disorder (OCD). Studies indicate that about 60-90% of people who undergo ERP experience a significant reduction in their OCD symptoms. The positive effects of ERP often persist, with many individuals continuing to feel better over time. Additionally, research confirms that ERP is generally safe, with no serious side effects reported. In this trial, participants will receive ERP alongside different employment services. One group will receive Standard Vocational Services plus ERP, while another group will receive Individual Placement and Support plus ERP. The study primarily focuses on how well ERP improves OCD symptoms.15678

Who Is on the Research Team?

SR

Sapana R Patel, Ph.D.

Principal Investigator

The New York State Psychiatric Institute

BS

Blair Simpson, MD, Ph.D.

Principal Investigator

The New York State Psychiatric Institute

Are You a Good Fit for This Trial?

This trial is for adults diagnosed with OCD who are currently unemployed and want to find regular work. If taking psychiatric medication, they must be on a stable dose and willing to keep it unchanged during therapy.

Inclusion Criteria

I have been diagnosed with OCD as my main condition.
I am not working and want to find a regular job.
I am on a stable dose of psychiatric medication and willing to keep it the same during CBT.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive Cognitive Behavioral Therapy (CBT) for OCD, consisting of exposure and response prevention over 12 weeks

12 weeks
Weekly sessions

Vocational Support

Participants receive either Standard Vocational Services (SVS) or Individual Placement and Support (IPS) for employment assistance over 12 months

12 months

Follow-up

Participants are monitored for work and clinical outcomes at 6, 9, and 12-month time points

12 months

What Are the Treatments Tested in This Trial?

Interventions

  • Exposure and Response Prevention
  • Individual Placement and Support (IPS)
  • Standard Vocational Services

Trial Overview

The study compares two job support programs—Individual Placement and Support (IPS) versus standard vocational services (SVS)—for people with OCD. All participants also receive up to 12 sessions of specialized CBT called exposure and response prevention.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Individual Placement and Support plus Cognitive Behavior Therapy for OCDExperimental Treatment1 Intervention
Group II: Standard Vocational Services plus Cognitive Behavioral Therapy for OCDActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

New York State Psychiatric Institute

Lead Sponsor

Trials
481
Recruited
154,000+

Citations

The effectiveness of exposure and response prevention ... - PMC

This study confirmed the feasibility of ERP combined with medication in improving obsessive-compulsive symptoms and depressive mood in patients with OCD, but ...

Exposure and Response Prevention in the Treatment of ... - PMC

Overall, about 50–60% of patients who complete ERP treatment show clinically significant improvement in OCD symptoms– and treatment gains have shown to be ...

An outcome study of an intensive, out-patient exposure and ...

We examined short- and long-term outcomes of the Melbourne Intensive Treatment-OCD (MIT-O) program, an out-patient intensive ERP program for OCD.

Exposure and Response Prevention for Obsessive ...

Research confirms that Ex/RP leads to major and lasting improvements in OCD symptoms. Reports indicate no serious side effects, making it a safe choice for many ...

Exposure Therapy in Mixed Reality for Obsessive ...

In this single-center randomized clinical trial including 36 patients, MERP did not significantly reduce OCD symptom severity compared with an active control ...

Exposure and response prevention for obsessive-compulsive ...

Although the current guidelines recommend ERP as the first-line treatment for OCD, only about half of the patients who receive it will reach complete symptom ...

The effectiveness of exposure and response prevention ...

Objective: To systematically evaluate the effectiveness of exposure and response prevention (ERP) combined with medication on obsessive-compulsive disorder (OCD) ...

Exposure and Response Prevention for OCD

Research has shown that Exposure and Response Prevention (ERP) is a safe and well-accepted treatment for people with obsessive-compulsive disorder (OCD).