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Behavioural Intervention

Personalized Assessments for Childhood OCD

Led By Joseph F. McGuire, PhD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be 8-17 years of age
Meet diagnostic criteria for a primary diagnosis of OCD on a structured clinical interview
Must not have
Inability to complete scales or attend visits
Screening 3 weeks
Treatment Varies
Follow Up screen, baseline (week 0), week 4, week 8, and week 12
Awards & highlights


"This trial aims to see if using a mobile app to assess OCD symptoms in children is helpful and acceptable for both the children and their parents. They will also see if personalized therapy based on these assessments works

Who is the study for?
This trial is for children and teens aged 8-17 with a primary diagnosis of OCD, as confirmed by an interview. They should have moderate OCD severity and be either medication-free or on a stable dose for at least 8 weeks. Participants must speak English but can't join if they're already in psychotherapy for OCD, have certain other mental health conditions, or are at immediate risk of harming themselves.Check my eligibility
What is being tested?
The study is testing whether using mobile tech to assess OCD symptoms in kids leads to better treatment outcomes. It compares personalized cognitive-behavioral therapy (CBT), tailored based on these assessments, against standard CBT typically used to treat youth with OCD.See study design
What are the potential side effects?
Since the interventions involve assessments and therapy sessions rather than medications, typical side effects associated with drugs aren't expected. However, discussing sensitive topics during therapy could cause temporary distress or emotional discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
I am between 8 and 17 years old.
I have been officially diagnosed with OCD.
I have not changed my medications in the last 8 weeks.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
I cannot fill out forms or go to appointments by myself.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~screen, baseline (week 0), week 4, week 8, and week 12
This trial's timeline: 3 weeks for screening, Varies for treatment, and screen, baseline (week 0), week 4, week 8, and week 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Children's Yale-Brown Obsessive-Compulsive Scale Second Edition (CY-BOCS-II) Total Severity Score

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Personalized AssessmentsExperimental Treatment1 Intervention
12 sessions of exposure with response prevention (ERP) that is guided by personalized assessments.
Group II: Standard of CareActive Control1 Intervention
12 sessions of exposure with response prevention (ERP) that is guided using standard practice.

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,285 Previous Clinical Trials
14,843,035 Total Patients Enrolled
1 Trials studying Obsessive-Compulsive Disorder
30 Patients Enrolled for Obsessive-Compulsive Disorder
Joseph F. McGuire, PhDPrincipal InvestigatorJohns Hopkins University
1 Previous Clinical Trials
3 Total Patients Enrolled
~20 spots leftby Jun 2025