Lifestyle Interventions for Obesity
(LiveWell Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this study is to examine the relationship in individuals with overweight/obesity and endocrine disrupting chemical (EDC) exposure through a two-armed, randomized clinical trial. The main questions this study aims to answer are:
1. If MM's 12-week EDC intervention program (EDC testing and report-back, EDC reduction curriculum) can reduce weight?
2. If a 12-week validated digital weight loss program can reduce EDC exposures?
3. What is the effectiveness of the two interventions at reducing weight and urinary EDC metabolites? Participants will be assigned to one of these two arms. Participants will collect their urine and blood samples pre- and post-intervention, and will take a comprehensive exposure survey before sending back their samples. This exposure survey will ask about participant's weight loss literacy, environmental health literacy, product use, diet, and lifestyle behaviors.
Who Is on the Research Team?
Johanna R Rochester, PhD
Principal Investigator
Million Marker Wellness
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants complete baseline surveys and receive test kits for urine and blood samples
Intervention
Participants engage in either a 12-week EDC reduction program or a digital weight loss program
Post-Intervention Assessment
Participants submit post-intervention samples and complete surveys
Follow-up
Participants are monitored for changes in EDC metabolites and weight-related health literacy
What Are the Treatments Tested in This Trial?
Interventions
- Weight Loss and EDC Reduction Program
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Individuals will be recruited to this following the same eligibility and recruitment parameters of the EDC intervention group. The weight loss intervention group will use a weight loss application for 12 weeks. Participants will receive a MM test kit and Siphox kit at baseline, before starting the weight loss intervention, and after 12 weeks of engaging with the weight loss program. They will not undergo any EDC lifestyle auditing. Additionally, in order to reduce bias, these participants will not receive the results of their EDC testing and recommendations for reducing exposure until after the study has been completed, at which point they will receive both their baseline and post-intervention EDC exposure results.
Participants will be required to attend 2 food/product/lifestyle audit sessions, complete at least 6 out 12 of the modules in the intervention course and complete pre-post intervention surveys. Participants will be guided through this journey from our online instructions, online video tutorials, extensive educational materials, and email communication.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Million Marker Wellness, Inc.
Lead Sponsor
National Institute of Environmental Health Sciences (NIEHS)
Collaborator
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.