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Imaging

Advanced MRI-Guided Biopsy for Brain Cancer

N/A

Recruiting

Led By Dawid Schellingerhout, MD

Research Sponsored by M.D. Anderson Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patient is a candidate for cerebral tumor resection with lesion suspected to be or previously biopsy proven to be a primary brain tumor

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 weeks

Awards & highlights

Study Summary

This trialstudies if using advanced MRI helps guide needle biopsies of brain tumors, and if the results of the MRI and biopsies match. Up to 50 patients will take part at MD Anderson, with no costs to them.

Who is the study for?

This trial is for adults over 18 with suspected or confirmed primary brain tumors who need a tumor resection. They must understand and consent to the study, have an MRI before surgery, and have adequate kidney function. It's not for those with MR-unsafe implants/devices, prior brain tumor treatments (except biopsy), claustrophobia unmanageable by medication, or certain non-CNS malignancies.Check my eligibility

What is being tested?

The study tests if advanced magnetic resonance imaging (AMRI) can better target needle biopsies of brain tumors than standard methods. Researchers will compare image results with biopsy findings to improve AMRI use in diagnosis. The perfusion scan used is investigational and only for research purposes.See study design

What are the potential side effects?

Potential side effects may include discomfort from the MRI procedure, risks associated with additional anesthesia during surgery, reactions to special pathology stains or gene testing materials used in the study. However, no specific side effects are listed related to the AMRI itself.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am eligible for surgery to remove a brain tumor.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Comparison of the Accuracy of the Pathological Grades of Tumor Observed at the Biopsy Locations Identified Using Conventional Versus Advanced Imaging

Target Sample Grading

Trial Design

1Treatment groups

Experimental Treatment

Group I: Advanced MR Imaging (AMRI) ScanExperimental Treatment2 Interventions

AMRI scan performed within 2 weeks before standard of care brain surgery. During the surgery, neurosurgeon(s) use the information collected from the AMRI to decide what area of the brain tumor will be biopsied.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor

2,974 Previous Clinical Trials

1,789,424 Total Patients Enrolled

Dawid Schellingerhout, MDPrincipal InvestigatorM.D. Anderson Cancer Center

2 Previous Clinical Trials

28 Total Patients Enrolled

Media Library

Advanced Magnetic Resonance Imaging Scan (Imaging) Clinical Trial Eligibility Overview. Trial Name: NCT03458676 — N/A

Brain Lesions Research Study Groups: Advanced MR Imaging (AMRI) Scan

Brain Lesions Clinical Trial 2023: Advanced Magnetic Resonance Imaging Scan Highlights & Side Effects. Trial Name: NCT03458676 — N/A

Advanced Magnetic Resonance Imaging Scan (Imaging) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03458676 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there vacancies available for prospective participants in this clinical trial?

"According to clinicaltrials.gov, this trial is ongoing and has been recruiting since September 6th 2012 with the most recent update occuring on September 27th 2022."

Answered by AI

How many individuals are enrolled in this experiment?

"Indeed, the information on clinicaltrials.gov indicates that this investigation is currently recruiting participants. It was first published on September 6th 2012 and recently updated on September 27th 2022, aiming to admit 50 individuals from one site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Radiologic Pathologic Correlation of Advanced MR Imaging to Guide the Biopsy of Cerebral Malignancies

2012. "Radiologic Pathologic Correlation of Advanced MR Imaging to Guide the Biopsy of Cerebral Malignancies". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03458676.