Advanced MRI-Guided Biopsy for Brain Cancer
Trial Summary
What is the purpose of this trial?
The goal of this clinical research study is to learn if using advanced magnetic resonance imaging (AMRI) will improve the targeting of brain tumor needle biopsies compared to the standard targeting techniques. Researchers also want to learn how the results of the images and biopsies compare to each other to try to improve the way researchers and radiologists use AMRI images. This is an investigational study. The perfusion scan is not FDA approved or commercially available. It is currently only being used in research. There will be no cost to you for the advanced MRI, additional anesthesia, special pathology stains, and/or gene testing for this study. Up to 50 patients will take part in this study. All will be enrolled at MD Anderson.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you have any implants or devices that are not safe for MRI, you may not be eligible to participate.
What data supports the effectiveness of the treatment Advanced MRI-Guided Biopsy for Brain Cancer?
Is the advanced MRI-guided biopsy for brain cancer safe?
Research shows that advanced MRI-guided biopsies, including frameless stereotactic techniques, are generally safe for humans. Studies found no major complications and confirmed the accuracy of the procedure, with the ability to correct any issues during surgery, making it a reliable and safe option for brain biopsies.678910
How is the Advanced MRI-Guided Biopsy treatment for brain cancer different from other treatments?
Research Team
Dawid Schellingerhout
Principal Investigator
M.D. Anderson Cancer Center
Eligibility Criteria
This trial is for adults over 18 with suspected or confirmed primary brain tumors who need a tumor resection. They must understand and consent to the study, have an MRI before surgery, and have adequate kidney function. It's not for those with MR-unsafe implants/devices, prior brain tumor treatments (except biopsy), claustrophobia unmanageable by medication, or certain non-CNS malignancies.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
AMRI Scan
Participants undergo an advanced MRI scan to improve targeting of brain tumor needle biopsies
Surgery and Biopsy
During surgery, neurosurgeons use AMRI information to decide biopsy locations. Biopsies are taken before tumor removal.
Follow-up
Participants continue standard of care follow-up appointments in the neurosurgery clinic
Treatment Details
Interventions
- Advanced Magnetic Resonance Imaging Scan
- Standard of Care Brain Biopsy and Tumor Removal
Advanced Magnetic Resonance Imaging Scan is already approved in United States for the following indications:
- Research Use Only
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor