Photoacoustic Imaging for Lymph Node Cancer
Trial Summary
What is the purpose of this trial?
This early phase I trial studies how well ultrasound-guided photoacoustic imaging works in telling the difference between healthy and cancerous inguinal (groin) lymph nodes and how well it can detect certain features of lymph nodes, including size and shape in patients with cancer. Ultrasound-guided photoacoustic is a non-invasive imaging method that can detect and display characteristics of lymph nodes based on the level of oxygen in the cells. This imaging method may provide more accurate tumor staging and prevent unnecessary surgical interventions.
Research Team
Priya R. Bhosale
Principal Investigator
M.D. Anderson Cancer Center
Eligibility Criteria
This trial is for cancer patients with suspicious groin lymph nodes identified by standard imaging and scheduled for needle aspiration or biopsy. It's not suitable for melanoma patients or those with deep (3-5 cm) or small (<1 cm) lymph nodes.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Imaging and Biopsy
Patients undergo standard of care ultrasound of the lymph nodes, then undergo ultrasound-guided photoacoustic imaging over 3-5 minutes, followed by standard of care ultrasound-guided fine needle aspiration or biopsy of a suspicious lymph node
Follow-up
Participants are monitored for safety and effectiveness after imaging and biopsy
Treatment Details
Interventions
- Fine-Needle Aspiration
- Lymph Node Biopsy
- Multispectral optoacoustic tomography (MSOT) acuity instrument
- Photoacoustic Imaging
- Ultrasound
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator