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Procedure

Diagnostic Lab Test During Pleuroscopy for Lung Cancer

N/A

Waitlist Available

Led By Horiana Grosu

Research Sponsored by M.D. Anderson Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patients who will undergo pleuroscopy with biopsy

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 1 year

Awards & highlights

Study Summary

This trialevaluates a new lab test to diagnose cancer in the linings of the lungs during a pleuroscopy.

Who is the study for?

This trial is for patients who are scheduled to undergo pleuroscopy with biopsy to check for cancerous fluid in the lung linings. It's not open to those already diagnosed with malignant pleural effusion or those who can't or won't consent.Check my eligibility

What is being tested?

The study tests a lab technique called rapid on site evaluation of pleural touch preparations, using samples from biopsies taken during pleuroscopy, to diagnose malignant pleural effusion quickly.See study design

What are the potential side effects?

Since this trial involves standard procedures like biopsy and thoracoscopy, potential side effects may include pain at the biopsy site, bleeding, infection risk, and discomfort from the thoracoscopy.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am scheduled for a pleuroscopy with biopsy.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Specificity of rapid on site evaluation (ROSE) of touch preparations (preps) for predicting malignancy

Secondary outcome measures

Negative predictive value (NPV) for all patients

Positive predictive value (PPV) for all patients

Sensitivity of ROSE of preps for predicting malignancy

+4 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Observational (pleuroscopy, medical chart review)Experimental Treatment3 Interventions

Patients undergo biopsy of the lining of the lung using pleuroscopy. Medical chart of patients is also reviewed.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Biopsy

2014

Completed Phase 4

~850

Thoracoscopy

2008

Completed Phase 3

~300

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor

2,966 Previous Clinical Trials

1,804,684 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,654 Previous Clinical Trials

40,933,056 Total Patients Enrolled

Horiana GrosuPrincipal InvestigatorM.D. Anderson Cancer Center

1 Previous Clinical Trials

80 Total Patients Enrolled

Media Library

Thoracoscopy (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT03868579 — N/A

Lung Cancer Research Study Groups: Observational (pleuroscopy, medical chart review)

Lung Cancer Clinical Trial 2023: Thoracoscopy Highlights & Side Effects. Trial Name: NCT03868579 — N/A

Thoracoscopy (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03868579 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any opportunities to enroll in this research endeavor at the moment?

"This study, which was posted on October 1st 2018 and last updated December 5th 2022, is not presently taking in patients. However, there are 2401 other trials that remain open for participant recruitment at this time."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy

2018. "Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03868579.

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