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Aerobic Exercise for Colorectal Cancer (RESTORE Trial)

N/A

Recruiting

Led By Justin C. Brown, Ph.D.

Research Sponsored by Pennington Biomedical Research Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to week 12

Awards & highlights

RESTORE Trial Summary

This trial will study how exercise affects fat around the muscles of colorectal cancer survivors.

Who is the study for?

This trial is for adults over 18 who've had stage I, II, or III colon or rectal cancer and finished their surgery and other treatments. They should exercise less than 150 minutes a week and not be planning any major surgeries during the study. Participants must be ready to start exercising, have a doctor's approval, agree to random assignment in the trial, and give written consent.Check my eligibility

What is being tested?

The study is looking at how regular aerobic exercise affects muscle changes in people who've survived colorectal cancer compared to those who just do stretching exercises. The main focus is on fat within muscles after completing cancer treatment.See study design

What are the potential side effects?

Aerobic exercise may cause general discomfort like muscle soreness or fatigue initially as participants adjust to increased physical activity levels.

RESTORE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to week 12

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to week 12

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to week 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Whole-Body Intermuscular Adipose Tissue

RESTORE Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Aerobic exerciseExperimental Treatment1 Intervention

Aerobic exercise at a dose of 225 minutes per week

Group II: Attention controlPlacebo Group1 Intervention

Static stretching

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Aerobic exercise

2000

Completed Phase 2

~1130

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Pennington Biomedical Research CenterLead Sponsor

305 Previous Clinical Trials

181,966 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,665 Previous Clinical Trials

40,925,784 Total Patients Enrolled

Justin C. Brown, Ph.D.Principal InvestigatorPennington Biomedical Research Center

1 Previous Clinical Trials

219 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals are being recruited to participate in this research?

"Affirmative. According to clinicaltrials.gov, this ongoing medical trial is open for enrollment; the study was first posted on May 1st 2023 and last updated on May 29th of the same year. Currently, there are 70 participants needed at one location."

Answered by AI

Is recruitment ongoing for this trial?

"Affirmative, the information hosted on clinicaltrials.gov indicates that this medical trial is presently recruiting participants. The initial post was recorded on May 1st 2023 and has since been updated as recently as May 29th 2023. In total, 70 patients need to be enrolled from one site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer

Justin Brown 2023. "Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05789433.

All > Colon Cancer > Rectal Cancer