WELL-MPN App for Myeloproliferative Neoplasms

(WELL-MPN Trial)

CH
Overseen ByChi-Joan How
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Brigham and Women's Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether a digital lifestyle app can assist people with myeloproliferative neoplasms (MPNs), a type of blood cancer, in improving their diet, exercise habits, and overall well-being. Participants will either use the WELL-MPN Digital App or receive written materials about healthy living with cancer. The trial aims to determine if the app better alleviates symptoms, improves mood, and boosts health management confidence compared to the written materials. Ideal participants are adults diagnosed with MPNs who can read and speak English. As an unphased trial, this study provides an opportunity to contribute to innovative research that could enhance the quality of life for those with MPNs.

What prior data suggests that the WELL-MPN app is safe for people with myeloproliferative neoplasms?

Research shows that digital apps like the WELL-MPN app, designed for people with myeloproliferative neoplasms (MPNs), are generally safe. Studies on similar apps have not identified any serious safety issues. These apps are well-tolerated because they focus on improving lifestyle habits, such as diet and exercise, rather than introducing new drugs or treatments. Participants typically find it easier to manage their symptoms and enhance their quality of life, with no major side effects reported. This suggests that using the WELL-MPN app is likely safe and beneficial for people with MPNs, based on past research with similar digital health tools.12345

Why are researchers excited about this trial?

Researchers are excited about the WELL-MPN Digital App because it offers a fresh approach to managing myeloproliferative neoplasms (MPNs) by integrating digital health technology into patient care. Unlike traditional treatments that focus solely on medication or standard care practices, this app aims to enhance patient engagement and self-management through personalized health tracking and educational resources. By providing patients with real-time feedback and guidance on diet and physical activity, the app could empower individuals to play a more active role in their treatment, potentially improving their quality of life and treatment outcomes.

What evidence suggests that the WELL-MPN app is effective for improving lifestyle and well-being in people with myeloproliferative neoplasms?

Research shows that digital lifestyle apps can help people with myeloproliferative neoplasms (MPNs) manage symptoms and improve quality of life. A small study found that using a wellness app reduced symptoms for MPN patients over 12 weeks. In this trial, participants will either use the WELL-MPN Digital App alongside usual care or receive enhanced usual care with written literature about diet and physical activity guidelines. These apps track and monitor health, aiding in better symptom management. By encouraging healthier eating and more physical activity, these apps may also enhance emotional well-being and overall quality of life for people with MPNs. Overall, early findings suggest that these apps can positively impact managing MPN-related challenges.14678

Who Is on the Research Team?

CH

Chi-Joan How

Principal Investigator

Massachusetts General Hospital

Are You a Good Fit for This Trial?

This trial is for adults over 18 with a myeloproliferative neoplasm (MPN) diagnosis as per WHO criteria, who can understand and speak English, and are able to give informed consent. Specific MPN conditions include Essential Thrombocythemia, Polycythemia Vera, and Myelofibrosis.

Inclusion Criteria

I have been diagnosed with a blood disorder according to WHO 2016 criteria.
I am 18 years old or older.
I can understand and agree to the study's procedures and risks.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants are randomly assigned to use the WELL-MPN app or receive written lifestyle education materials and use the assigned program over the study period

16 weeks
Regular app usage and survey completion

Follow-up

Participants are monitored for improvements in lifestyle behaviors, symptoms, and well-being

16 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • WELL-MPN Digital App

Trial Overview

The WELL-MPN digital app is being tested to see if it improves diet, physical activity, symptoms, emotional well-being, and quality of life in MPN patients. Participants will either use the app or receive written educational materials on lifestyle behaviors.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: WELL-MPN Digital AppExperimental Treatment1 Intervention
Group II: Enhanced Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Brigham and Women's Hospital

Lead Sponsor

Trials
1,694
Recruited
14,790,000+

Citations

WELL-MPN: A Digital Lifestyle App for Patients With MPNs

The goal of this clinical trial is to learn whether a digital lifestyle app can help improve diet, physical activity, symptoms, ...

Pilot Feasibility and Acceptability Study

This study aims to determine the feasibility of a 12-week global wellness mobile app intervention in decreasing MPN symptom burden. The University of Arizona ...

Learn more about MY MPN VOICE APP

A smartphone application (app) designed to track and monitor your health, could potentially improve your symptom management and quality of life as an MPN ...

MPN CONSENSUS REPORT

EMPOWERING PATIENTS, ENHANCING OUTCOMES: EFFECTIVE COMMUNICATION IN MPN CARE. “MPN specialists play a very specific role in the care of patients. In order ...

Applications of artificial intelligence to myeloproliferative ...

In this narrative review, we discuss AI investigations for the improvement of MPN clinical care utilizing either clinically available data or experimental ...

WELL-MPN: A Digital Lifestyle App for Patients With MPNs

The goal of this clinical trial is to learn whether a digital lifestyle app can help improve diet, physical activity, symptoms, ...

Mobile App Intervention on Reducing the Myeloproliferative ...

This study aims to determine the feasibility of a 12-week global wellness mobile app intervention in decreasing MPN symptom burden.

Mobile App Intervention on Reducing the ...

This study aims to determine the feasibility of a 12-week global wellness mobile app intervention in decreasing MPN symptom burden.