Motor Skill and Strength Training for Spinal Muscular Atrophy
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores the impact of a new treatment approach for children with spinal muscular atrophy (SMA), a condition that weakens muscles. The trial combines two therapies: HABIT-ILE, which improves hand and leg coordination, and Functional Strength Training, which increases muscle strength. The goal is to determine if this combination can enhance motor skills in children already on stable disease-modifying therapies. Children with SMA who understand English and have been on steady treatment for at least six months might be suitable candidates. As an unphased trial, this study provides a unique opportunity to contribute to innovative research that could enhance treatment options for SMA.
Do I need to stop my current medications to join the trial?
You don't need to stop your current medications, but you must be on a stable dose of your disease-modifying therapy for at least 6 months before joining the trial.
What prior data suggests that this motor skill and strength training intervention is safe for children with SMA?
Studies have shown that HABIT-ILE (Hand-Arm Bimanual Intensive Therapy Including Lower Extremities) combined with Functional Strength Training (FST) is generally well-tolerated in children with spinal muscular atrophy (SMA). This intensive training program improves motor skills and strength. Research indicates no major side effects have been reported in previous studies with similar treatments. Participants typically experience only mild discomfort, such as muscle soreness, which is common with any new physical activity. This suggests the treatment is safe for children receiving therapies for SMA.12345
Why are researchers excited about this trial?
Researchers are excited about HABIT-ILE + FST for Spinal Muscular Atrophy (SMA) because it combines two innovative therapies into one intensive program. Unlike traditional treatments that may focus on medication or isolated physical therapy exercises, this approach integrates Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) with Functional Strength Training (FST). This dual approach aims to improve both upper and lower limb function through a comprehensive, motor learning-based program. By delivering the treatment in a camp format, participants receive focused, immersive therapy that could lead to more significant improvements in motor skills compared to current options.
What evidence suggests that the HABIT-ILE + FST intervention is effective for improving motor skills in children with SMA?
Research has shown that combining two types of therapy—Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) and Functional Strength Training (FST)—can improve motor skills in children with Spinal Muscular Atrophy (SMA). In this trial, participants will receive this combined intervention, which studies have found enhances the function of both arms and legs. Children receiving treatments that modify the disease have shown particularly good results with this intensive training. The program focuses on learning to move better, which improves muscle coordination and strength. These early findings are promising for enhancing movement abilities in kids with SMA.12345
Are You a Good Fit for This Trial?
This trial is for children with Spinal Muscular Atrophy (SMA) who are already on disease-modifying therapies. Specific eligibility criteria were not provided, so it's important to contact the study organizers for detailed inclusion and exclusion information.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a combined intervention of HABIT-ILE and FST for 6 hours each weekend over 15 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- HABIT-ILE + FST
Trial Overview
The trial tests a combination of intensive motor skill therapy called HABIT-ILE and functional strength training (FST). Children will participate in one 6-hour session each weekend for 15 weeks, totaling 90 hours of training. The focus is on feasibility and improving motor skills.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Participants receive a combined intervention consisting of Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) and Functional Strength Training (FST). Both components are delivered as an integrated, intensive motor learning-based program aimed at improving upper and lower limb function in children with SMA .Subject will participate in a HABIT-ILE + FST camp format for 6 hours/day, one day/week for 15 weeks.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Teachers College, Columbia University
Lead Sponsor
Citations
NCT07223320 | HABIT-ILE + FST in Children With SMA
Participants will attend one 6-hour HABIT-ILE + FST session each weekend (Saturday or Sunday) for 15 weeks, for a total of 90 hours of training. Feasibility ...
HABIT-ILE + FST in Children With SMA
The aim of this pilot proposal is to evaluate the feasibility and preliminary efficacy of HABIT-ILE + FST in children with SMA receiving DMTs.
HABIT-ILE + FST in Children With SMA
Combined Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) + functional strength training (FST). See if you qualify. Study Details.
HABIT-ILE + FST in Children With SMA
Combined HABIT-ILE + FST. Participants receive a combined intervention consisting of Hand-Arm Bimanual Intensive Therapy Including Lower ...
HABIT-ILE + FST in Children With SMA
Back to study results. A pilot interventional study of HABIT-ILE + FST in children with SMA. A study testing intensive motor skills training ...
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.