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Nutritional Intervention

Nutritional Intervention for Anterior Cruciate Ligament Reconstruction

N/A

Recruiting

Led By Chris McGlory, PhD

Research Sponsored by Dr. Chris McGlory, PhD

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosed anterior cruciate ligament injury requiring reconstruction surgery

Patellar tendon graft or quadriceps tendon graft reconstruction procedure

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 18 months and 12 weeks (8 weeks post surgery), respectively.

Awards & highlights

Study Summary

"This trial aims to investigate whether a combination of essential amino acids and omega-3 fatty acids can help prevent muscle loss and weakness after knee surgery. The study will involve participants taking these supplements before and after

Who is the study for?

This trial is for adults with a diagnosed anterior cruciate ligament injury who are scheduled for reconstruction surgery using patellar or quadriceps tendon grafts in Kingston, ON. It's designed to see if certain nutritional supplements can help prevent muscle loss after knee surgery.Check my eligibility

What is being tested?

The study tests whether taking omega-3 fatty acids and essential amino acids can reduce muscle atrophy compared to a control group taking safflower oil and non-essential amino acids. Participants will start the supplements 4 weeks before surgery and continue for 2 weeks after.See study design

What are the potential side effects?

Potential side effects may include digestive discomfort or allergic reactions related to the supplement ingredients like omega-3 fatty acids or amino acids. However, these are generally considered safe.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I need surgery for a torn ACL in my knee.

Select...

I had knee surgery using a patellar or quadriceps tendon graft.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 18 months and 12 weeks (8 weeks post surgery), respectively.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~18 months and 12 weeks (8 weeks post surgery), respectively.

This trial's timeline: 3 weeks for screening, Varies for treatment, and 18 months and 12 weeks (8 weeks post surgery), respectively. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Feasibility of Recruitment and Retention

Secondary outcome measures

Erythrocyte Phospholipid Composition

Expression of Translational Factors Related to Skeletal Muscle Protein Synthesis

Muscle Cross-Sectional Area

+9 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Nutritional InterventionExperimental Treatment1 Intervention

5 g omega-3 fatty acids (3.75 g eicosapentaenoic acid [EPA] + 1.25 g docosahexaenoic acid [DHA]) per day for 6 weeks, starting 4 weeks before and continuing 2 weeks after surgery, plus 40 g (2 x 20 g) of EAA per day, starting 1 week before and continuing 2 weeks after surgery.

Group II: Placebo ControlPlacebo Group1 Intervention

5 g safflower oil per day for 6 weeks, starting 4 weeks before and continuing 2 weeks after surgery, plus 40 g (2 x 20 g) of NEAA per day, starting 1 week before and continuing 2 weeks after surgery.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Dr. Chris McGlory, PhDLead Sponsor

2 Previous Clinical Trials

48 Total Patients Enrolled

Chris McGlory, PhDPrincipal InvestigatorQueen's University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current number of individuals being admitted into this particular medical trial?

"Indeed, the current data on clinicaltrials.gov demonstrates that this trial is actively seeking candidates. The study first appeared on 2/1/2024 and was last revised on 2/6/2024. A total of 30 participants are sought at a single research site."

Answered by AI

Are researchers currently recruiting participants for this ongoing medical study?

"Indeed, data from clinicaltrials.gov highlights the ongoing recruitment of participants for this trial. Initially shared on February 1st, 2024 and revised lastly on February 6th, 2024, the study is seeking to enroll a total of 30 individuals at one designated site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Nutritional Intervention to Enhance Recovery After Arthroscopic Knee Surgery in Adults

Dr. Chris McGlory, PhD 2024. "Nutritional Intervention to Enhance Recovery After Arthroscopic Knee Surgery in Adults". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06233825.

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