10 Participants NeededMy employer runs this trial

Skeletal Muscle Aging and Responsiveness in Aged People With MS

(MS-M3AX Trial)

LF
BM
Overseen ByBobbette Miller
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Oklahoma Medical Research Foundation
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purposes of this study are to: 1) compare baseline muscle and cardiovascular health in older individuals (\>60 years old) diagnosed with MS to age-matched people without MS, 2) determine muscle and whole body changes to an exercise training program, 3) determine if the muscle in a more affected leg in individuals diagnosed with MS is different from the muscle of a less affected leg, and 4) if or how individuals diagnosed with MS adapt differently than age-matched people without MS to exercise training. Participation in this study will average 1.5 hours per visit, 3 visits per week, for approximately 4 months.

Who Is on the Research Team?

BF

Benjamin F Miller, Ph.D.

Principal Investigator

Oklahoma Medical Research Foundation

GP

Gabriel Pardo

Principal Investigator

Oklahoma Medical Research Foundation

Are You a Good Fit for This Trial?

Inclusion Criteria

* 1\. Male or female aged 60 or above 2. Free of unmanaged chronic diseases other than multiple sclerosis 3. No structured exercise program (2 or more bouts/wk) within previous 6 months 4. Cognitively capable of providing informed consent 5. Must meet EDSS score between 2 to 5.5 during screening

What Are the Treatments Tested in This Trial?

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: People with MSExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Oklahoma Medical Research Foundation

Lead Sponsor

Trials
24
Recruited
8,400+