Prehabilitation Program for Multiple Myeloma
Trial Summary
What is the purpose of this trial?
This is a pilot feasibility trial among older adults (≥60y) scheduled to undergo Autologous Stem Cell transplantation at UAB. Participants will be randomized into either a prehabilitation program or an attention control group before their transplant. The primary outcomes will be feasibility and secondary outcomes include changes in physical function at the time of transplant and at 12 weeks follow up.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the Prehabilitation Program for Multiple Myeloma treatment?
Research shows that exercise programs can help patients with multiple myeloma improve physical performance and reduce fatigue. Studies have also found that tailored exercise and lifestyle advice can increase physical activity and satisfaction among patients. Additionally, prehabilitation (exercise before treatment) has been effective in other diseases, suggesting potential benefits for multiple myeloma patients.12345
Is the Prehabilitation Program for Multiple Myeloma safe for humans?
How is the Prehabilitation Program for Multiple Myeloma different from other treatments?
The Prehabilitation Program for Multiple Myeloma is unique because it focuses on preparing patients for stem-cell transplantation through a combination of dietary guidelines and a multi-modal exercise regimen, which is not typically part of standard myeloma treatments. This approach aims to improve patients' physical conditioning before treatment, potentially enhancing recovery and long-term health outcomes.24569
Eligibility Criteria
This trial is for individuals aged 60 or older who have been diagnosed with Multiple Myeloma and are scheduled to undergo Autologous Stem Cell Transplantation (ASCT) at UAB within the next 10 weeks. Those at high risk for imminent bone fractures as determined by Mirels score cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Prehabilitation/Attention Control
Participants undergo an 8-week prehabilitation exercise program or receive nutrition counseling as an attention control
Transplantation
Participants undergo Autologous Stem Cell Transplant
Follow-up
Participants are monitored for changes in physical function and other outcomes post-transplant
Treatment Details
Interventions
- Dietary Guidelines
- Multi-modal Exercise Regimen
Find a Clinic Near You
Who Is Running the Clinical Trial?
Noha Mohamed Sharafeldin
Lead Sponsor
Smith Giri
Lead Sponsor