7 Participants Needed

Memory Support System for Mild Cognitive Impairment

CL
XZ
Overseen ByXinyi Zhang, MA
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Icahn School of Medicine at Mount Sinai
Must be taking: Memory-enhancing medications
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a Memory Support System to determine its effectiveness for Chinese American adults with mild cognitive impairment. Researchers aim to understand if this non-drug program benefits individuals who primarily speak Mandarin or Cantonese. Participants will either receive guided training with a day planner or engage in self-study and brain health education. The study seeks Chinese American individuals with mild memory issues who regularly speak Mandarin or Cantonese. As an unphased trial, it offers a unique opportunity to contribute to research that may enhance memory support for the community.

Will I have to stop taking my current medications?

The trial requires that you have either not been taking memory-enhancing medications or have been on a stable dose for the last 3 months. If you are on such medications, you don't need to stop them, but they should be stable.

What prior data suggests that the Memory Support System is safe for Chinese American older adults with mild cognitive impairment?

Research has shown that the Memory Support System (MSS) is a well-researched program designed to assist individuals with mild memory problems. It employs a calendar and notebook to address memory issues. Studies have found MSS to be safe and easy for participants to use, with no reports of harmful side effects. This is likely because it is a non-drug treatment focusing on behavioral strategies.

In past research, MSS helped users improve their daily memory tasks without negative effects. Participants can feel confident about the safety of joining MSS programs.12345

Why are researchers excited about this trial?

Researchers are excited about the Memory Support System (MSS) for mild cognitive impairment because it offers a structured, non-drug approach to improve memory. Unlike current treatments that often rely on medications, which can have side effects, the MSS involves personalized training sessions using a workbook to enhance cognitive skills. This method empowers individuals to actively engage in their cognitive health and adapt strategies that best fit their daily lives. Additionally, the ability to customize the number of sessions provides flexibility, allowing participants to receive support tailored to their needs.

What evidence suggests that the Memory Support System is effective for mild cognitive impairment?

Research has shown that the Memory Support System (MSS), which participants in this trial may receive, helps people with mild memory problems improve their daily activities and feel more confident about their memory. In some cases, these improvements last up to eight weeks after training. One study found that using MSS helped people remember names and faces better. This suggests that MSS can effectively boost memory skills for those with early memory issues. Overall, MSS appears to be a promising tool for supporting memory and daily skills in people experiencing early memory challenges.26789

Who Is on the Research Team?

CL

Clara Li, PhD

Principal Investigator

Icahn School of Medicine at Mount Sinai

Are You a Good Fit for This Trial?

This trial is for older Chinese American adults with mild cognitive impairment who primarily speak Mandarin or Cantonese. They need a study partner to join them. There's no mention of specific exclusions, so it seems open to those fitting the language and cognitive criteria.

Inclusion Criteria

Self-identify as Chinese American
Able to read and write in Chinese
I am 55 years old or older.
See 6 more

Exclusion Criteria

I do not have any major nerve-related diseases that would stop me from completing the trial.
History of psychiatry disorder (DSM 5 criteria) within the last 12 months
History of reading or writing disability sufficient to interfere with MSS training
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either the MSS Training Workbook or Brain Health Education over 10-15 sessions

4-9 weeks
10-15 sessions

Follow-up

Participants are monitored for safety and effectiveness after treatment

8 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Memory Support System
Trial Overview The study tests a Memory Support System (MSS) designed to help with memory problems in older adults. Participants will either receive trainer-led day planner training or self-study the day planner alongside brain health education.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: MSS Intervention GroupExperimental Treatment1 Intervention
Group II: Brain Health Education Control GroupActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Icahn School of Medicine at Mount Sinai

Lead Sponsor

Trials
933
Recruited
579,000+

Citations

The Memory Support System for Mild Cognitive ImpairmentMSS training resulted in improvement in ADLs and sense of memory self efficacy for individuals with MCI. While ADL benefits were maintained out to 8 weeks post ...
A review of the effectiveness of memory interventions ...Explicit memory training leads to improved memory for face-name pairs in patients with mild cognitive impairment: results of a pilot investigation. Journal ...
The Learning of Memory Support System in Individuals with ...Conclusion. Participants with MD-aMCI showed poorer MSS learning efficiency than participants with SD-aMCI. Etiology did not impact MSS learning ...
NCT05999929 | Memory Support System Feasibility StudyThe purpose of this study is to determining the feasibility of providing the Memory Support System (MSS) to individuals with mild cognitive impairment (MCI) ...
Comparative Effectiveness of Behavioral Interventions on ...This study offers a starting point for understanding which behavioral interventions are most effective for patient- and partner-desired outcomes in mild ...
A Rehabilitation Intervention for Amnestic Mild Cognitive ...The overall goal of this pilot project is to refine delivery of the Memory Support System (MSS)as a formal compensatory program for memory loss ...
Implementation of the Memory Support System for ...The Memory Support System (MSS), an evidence-based behavioral intervention developed by the Mayo Clinic, has been shown to aid those living with MCI and their ...
Mild Cognitive Impairment (MCI) Clinical TrialsThe purpose of this study is to develop a linguistically and culturally- appropriate adaptation of the memory support system (MSS) for Spanish-speaking ...
Behavioral Interventions in Mild Cognitive Impairment (MCI)Memory support system (MSS) training: This intervention for MCI, pioneered by Greenaway et al. [23, 24], involves intensive training to use a calendaring/ ...
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